HAO1

GENE INFORMATION

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Gene name

HAO1 (HGNC Symbol)

Synonyms

GOX, GOX1

Description

Hydroxyacid oxidase (glycolate oxidase) 1 (HGNC Symbol)

Entrez gene summary

This gene is one of three related genes that have 2-hydroxyacid oxidase activity yet differ in encoded protein amino acid sequence, tissue expression and substrate preference. Subcellular location of the encoded protein is the peroxisome. Specifically, this gene is expressed primarily in liver and pancreas and the encoded protein is most active on glycolate, a two-carbon substrate. The protein is also active on 2-hydroxy fatty acids. The transcript detected at high levels in pancreas may represent an alternatively spliced form or the use of a multiple near-consensus upstream polyadenylation site. [provided by RefSeq, Jul 2008]

Chromosome

20

Cytoband

p12.3

Chromosome location (bp)

7882981 - 7940474

Protein evidence

Evidence at protein level (all genes)

Ensembl

ENSG00000101323 (version 78.38)

Entrez gene

54363

UniProt

Q9UJM8 (UniProt - Evidence at protein level)

neXtProt

NX_Q9UJM8

Antibodypedia

HAO1 antibodies
 

PROTEIN VIEW

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HAO1-001
 
 
 
 
 

PROTEIN INFORMATION

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Splice variant

Ensembl

UniProt

Protein class

Gene ontology

Length
(aa)

Molecular mass
(kDa)

Signal peptide
(predicted)

Transmembrane regions
(predicted)

HAO1-001 ENSP00000368066
ENST00000378789
Q9UJM8
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