SIRPB1

GENE INFORMATION

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Gene name

SIRPB1 (HGNC Symbol)

Synonyms

CD172b, SIRP-BETA-1

Description

Signal-regulatory protein beta 1 (HGNC Symbol)

Entrez gene summary

The protein encoded by this gene is a member of the signal-regulatory-protein (SIRP) family, and also belongs to the immunoglobulin superfamily. SIRP family members are receptor-type transmembrane glycoproteins known to be involved in the negative regulation of receptor tyrosine kinase-coupled signaling processes. This protein was found to interact with TYROBP/DAP12, a protein bearing immunoreceptor tyrosine-based activation motifs. This protein was also reported to participate in the recruitment of tyrosine kinase SYK. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Feb 2009]

Chromosome

20

Cytoband

p13

Chromosome location (bp)

1563521 - 1620061

Protein evidence

Evidence at protein level (all genes)

Ensembl

ENSG00000101307 (version 78.38)

Entrez gene

10326

UniProt

O00241 (UniProt - Evidence at protein level), Q5TFQ8 (UniProt - Evidence at protein level)

neXtProt

NX_O00241, NX_Q5TFQ8

Antibodypedia

SIRPB1 antibodies
 

PROTEIN VIEW

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SIRPB1-001
 
SIRPB1-002
 
SIRPB1-003
 
SIRPB1-005
 
SIRPB1-006
 
SIRPB1-007
 
SIRPB1-008
 
SIRPB1-009
 
SIRPB1-011
 
SIRPB1-012
 
SIRPB1-014
 
SIRPB1-201
 
 » 
 
 
 
 

PROTEIN INFORMATION

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Splice variant

Ensembl

UniProt

Protein class

Gene ontology

Length
(aa)

Molecular mass
(kDa)

Signal peptide
(predicted)

Transmembrane regions
(predicted)

SIRPB1-001 ENSP00000371018
ENST00000381605
O00241
Show all »
Show » Show » 398 43.2 Yes 1
SIRPB1-002 ENSP00000371016
ENST00000381603
O00241
Show all »
Show » Show » 181 19.4 Yes 1
SIRPB1-003 ENSP00000279477
ENST00000279477
Q5TFQ8
Show all »
Show » Show » 398 43.4 Yes 1
SIRPB1-005 ENSP00000456826
ENST00000568365
Q5TFQ8
Show all »
Show » Show » 398 43.4 Yes 1
SIRPB1-006 ENSP00000457323
ENST00000569629
H3BTT9
Show all »
Show » 58 6.1 No 1
SIRPB1-007 ENSP00000456519
ENST00000569387
H3BU43
Show all »
Show » 77 8.2 No 1
SIRPB1-008 ENSP00000457458
ENST00000566055
H3BU43
Show all »
Show » 77 8.2 No 1
SIRPB1-009 ENSP00000457855
ENST00000565087
H3BU43
Show all »
Show » 77 8.2 No 1
SIRPB1-011 ENSP00000456351
ENST00000563840
H3BRP9
Show all »
Show » Show » 156 16.6 Yes 0
SIRPB1-012 ENSP00000457829
ENST00000565076
H3BUW0
Show all »
Show » Show » 182 20 No 0
SIRPB1-014 ENSP00000455568
ENST00000562014
H3BQ21
Show all »
Show » Show » 236 26 No 1
SIRPB1-201 ENSP00000262929
ENST00000262929
H9KV29
Show all »
Show » Show » 180 19.2 Yes 1