RSPO4

GENE INFORMATION

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Gene name

RSPO4 (HGNC Symbol)

Synonyms

C20orf182, dJ824F16.3

Description

R-spondin 4 (HGNC Symbol)

Entrez gene summary

This gene encodes a member of the R-spondin family of proteins that share a common domain organization consisting of a signal peptide, cysteine-rich/furin-like domain, thrombospondin domain and a C-terminal basic region. The encoded protein may be involved in activation of Wnt/beta-catenin signaling pathways. Mutations in this gene are associated with anonychia congenital. Alternate splicing results in multiple transcript variants.[provided by RefSeq, Sep 2009]

Chromosome

20

Cytoband

p13

Chromosome location (bp)

958452 - 1002264

Protein evidence

Evidence at protein level (all genes)

Ensembl

ENSG00000101282 (version 78.38)

Entrez gene

343637

UniProt

Q2I0M5 (UniProt - Evidence at protein level)

neXtProt

NX_Q2I0M5

Antibodypedia

RSPO4 antibodies
 

PROTEIN VIEW

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RSPO4-001
 
RSPO4-002
 
 
 
 
 

PROTEIN INFORMATION

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Splice variant

Ensembl

UniProt

Protein class

Gene ontology

Length
(aa)

Molecular mass
(kDa)

Signal peptide
(predicted)

Transmembrane regions
(predicted)

RSPO4-001 ENSP00000217260
ENST00000217260
Q2I0M5
Show all »
Show » Show » 234 26.2 Yes 0
RSPO4-002 ENSP00000383475
ENST00000400634
Q2I0M5
Show all »
Show » Show » 172 19.6 Yes 0