Splice variant |
Ensembl |
UniProt |
Protein class |
Gene ontology |
Length (aa) |
Molecular mass (kDa) |
Signal peptide (predicted) |
Transmembrane regions (predicted)
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MTHFD1-001 |
ENSP00000450560
ENST00000555709
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P11586 Show all »
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P11586 [Direct mapping]C-1-tetrahydrofolate synthase, cytoplasmic Methylenetetrahydrofolate dehydrogenase Methenyltetrahydrofolate cyclohydrolase Formyltetrahydrofolate synthetase C-1-tetrahydrofolate synthase, cytoplasmic, N-terminally processed V9GY75 [Target identity:26%; Query identity:100%]C-1-tetrahydrofolate synthase, cytoplasmic {ECO:0000313|Ensembl:ENSP00000476468} V9GZ78 [Target identity:9%; Query identity:100%]C-1-tetrahydrofolate synthase, cytoplasmic {ECO:0000313|Ensembl:ENSP00000477501} V9GZ32 [Target identity:8%; Query identity:100%]C-1-tetrahydrofolate synthase, cytoplasmic {ECO:0000313|Ensembl:ENSP00000477359}
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Enzymes ENZYME proteins Oxidoreductases Hydrolases Ligase Phobius predicted membrane proteins TMHMM predicted membrane proteins SPOCTOPUS predicted secreted proteins Predicted intracellular proteins Plasma proteins Disease related genes Potential drug targets Protein evidence (Kim et al 2014) Protein evidence (Ezkurdia et al 2014)
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261 |
28.2 |
No |
0 |
MTHFD1-002 |
ENSP00000438588
ENST00000545908
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F5H2F4 Show all »
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F5H2F4 [Target identity:100%; Query identity:100%]C-1-tetrahydrofolate synthase, cytoplasmic {ECO:0000313|Ensembl:ENSP00000438588} V9GY75 [Target identity:6%; Query identity:100%]C-1-tetrahydrofolate synthase, cytoplasmic {ECO:0000313|Ensembl:ENSP00000476468} V9GZ32 [Target identity:2%; Query identity:100%]C-1-tetrahydrofolate synthase, cytoplasmic {ECO:0000313|Ensembl:ENSP00000477359} V9GZ78 [Target identity:2%; Query identity:100%]C-1-tetrahydrofolate synthase, cytoplasmic {ECO:0000313|Ensembl:ENSP00000477501}
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Predicted membrane proteins Prediction method-based Membrane proteins predicted by MDM MEMSAT3 predicted membrane proteins MEMSAT-SVM predicted membrane proteins SCAMPI predicted membrane proteins SPOCTOPUS predicted membrane proteins TMHMM predicted membrane proteins # TM segments-based 1TM proteins predicted by MDM Protein evidence (Kim et al 2014) Protein evidence (Ezkurdia et al 2014)
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1020 |
110.6 |
No |
1 |
MTHFD1-005 |
ENSP00000477501
ENST00000554768
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V9GZ78 Show all »
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V9GZ78 [Target identity:100%; Query identity:100%]C-1-tetrahydrofolate synthase, cytoplasmic {ECO:0000313|Ensembl:ENSP00000477501} V9GZ32 [Target identity:92%; Query identity:100%]C-1-tetrahydrofolate synthase, cytoplasmic {ECO:0000313|Ensembl:ENSP00000477359}
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Predicted intracellular proteins Protein evidence (Kim et al 2014) Protein evidence (Ezkurdia et al 2014)
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GO:0003824 [catalytic activity] GO:0004488 [methylenetetrahydrofolate dehydrogenase (NADP+) activity] GO:0009396 [folic acid-containing compound biosynthetic process] GO:0055114 [oxidation-reduction process]
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25 |
2.8 |
No |
0 |
MTHFD1-006 |
ENSP00000476468
ENST00000557539
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V9GY75 Show all »
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V9GY75 [Target identity:100%; Query identity:100%]C-1-tetrahydrofolate synthase, cytoplasmic {ECO:0000313|Ensembl:ENSP00000476468} V9GZ78 [Target identity:36%; Query identity:100%]C-1-tetrahydrofolate synthase, cytoplasmic {ECO:0000313|Ensembl:ENSP00000477501} V9GZ32 [Target identity:33%; Query identity:100%]C-1-tetrahydrofolate synthase, cytoplasmic {ECO:0000313|Ensembl:ENSP00000477359}
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Predicted intracellular proteins Protein evidence (Kim et al 2014) Protein evidence (Ezkurdia et al 2014)
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GO:0003824 [catalytic activity] GO:0004488 [methylenetetrahydrofolate dehydrogenase (NADP+) activity] GO:0009396 [folic acid-containing compound biosynthetic process] GO:0055114 [oxidation-reduction process]
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68 |
7.3 |
No |
0 |
MTHFD1-014 |
ENSP00000477199
ENST00000557370
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V9GYY3 Show all »
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V9GYY3 [Target identity:100%; Query identity:100%]C-1-tetrahydrofolate synthase, cytoplasmic {ECO:0000313|Ensembl:ENSP00000477199}
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SPOCTOPUS predicted membrane proteins Predicted intracellular proteins Protein evidence (Kim et al 2014) Protein evidence (Ezkurdia et al 2014)
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107 |
11.5 |
No |
0 |
MTHFD1-015 |
ENSP00000477359
ENST00000554739
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V9GZ32 Show all »
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V9GZ32 [Target identity:100%; Query identity:100%]C-1-tetrahydrofolate synthase, cytoplasmic {ECO:0000313|Ensembl:ENSP00000477359}
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Predicted intracellular proteins Protein evidence (Kim et al 2014) Protein evidence (Ezkurdia et al 2014)
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GO:0003824 [catalytic activity] GO:0004488 [methylenetetrahydrofolate dehydrogenase (NADP+) activity] GO:0009396 [folic acid-containing compound biosynthetic process] GO:0055114 [oxidation-reduction process]
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23 |
2.6 |
No |
0 |
MTHFD1-019 |
ENSP00000216605
ENST00000216605
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P11586 Show all »
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P11586 [Direct mapping]C-1-tetrahydrofolate synthase, cytoplasmic Methylenetetrahydrofolate dehydrogenase Methenyltetrahydrofolate cyclohydrolase Formyltetrahydrofolate synthetase C-1-tetrahydrofolate synthase, cytoplasmic, N-terminally processed V9GY75 [Target identity:7%; Query identity:100%]C-1-tetrahydrofolate synthase, cytoplasmic {ECO:0000313|Ensembl:ENSP00000476468} V9GZ32 [Target identity:2%; Query identity:100%]C-1-tetrahydrofolate synthase, cytoplasmic {ECO:0000313|Ensembl:ENSP00000477359} V9GZ78 [Target identity:2%; Query identity:100%]C-1-tetrahydrofolate synthase, cytoplasmic {ECO:0000313|Ensembl:ENSP00000477501}
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Enzymes ENZYME proteins Oxidoreductases Hydrolases Ligase MEMSAT3 predicted membrane proteins MEMSAT-SVM predicted membrane proteins SCAMPI predicted membrane proteins SPOCTOPUS predicted membrane proteins Predicted intracellular proteins Plasma proteins Disease related genes Potential drug targets Protein evidence (Kim et al 2014) Protein evidence (Ezkurdia et al 2014)
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935 |
101.5 |
No |
0 |