CTSG

GENE INFORMATION

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Gene name

CTSG (HGNC Symbol)

Synonyms

CG

Description

Cathepsin G (HGNC Symbol)

Entrez gene summary

The protein encoded by this gene, a member of the peptidase S1 protein family, is found in azurophil granules of neutrophilic polymorphonuclear leukocytes. The encoded protease has a specificity similar to that of chymotrypsin C, and may participate in the killing and digestion of engulfed pathogens, and in connective tissue remodeling at sites of inflammation. In addition, the encoded protein is antimicrobial, with bacteriocidal activity against S. aureus and N. gonorrhoeae. Transcript variants utilizing alternative polyadenylation signals exist for this gene. [provided by RefSeq, Sep 2014]

Chromosome

14

Cytoband

q12

Chromosome location (bp)

24573522 - 24576260

Protein evidence

Evidence at protein level (all genes)

Ensembl

ENSG00000100448 (version 78.38)

Entrez gene

1511

UniProt

P08311 (UniProt - Evidence at protein level)

neXtProt

NX_P08311

Antibodypedia

CTSG antibodies
 

PROTEIN VIEW

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CTSG-001
 
 
 
 
 

PROTEIN INFORMATION

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Splice variant

Ensembl

UniProt

Protein class

Gene ontology

Length
(aa)

Molecular mass
(kDa)

Signal peptide
(predicted)

Transmembrane regions
(predicted)

CTSG-001 ENSP00000216336
ENST00000216336
P08311
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