SUN2

GENE INFORMATION

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Gene name

SUN2 (HGNC Symbol)

Synonyms

UNC84B

Description

Sad1 and UNC84 domain containing 2 (HGNC Symbol)

Entrez gene summary

SUN1 (MIM 607723) and SUN2 are inner nuclear membrane (INM) proteins that play a major role in nuclear-cytoplasmic connection by formation of a 'bridge' across the nuclear envelope, known as the LINC complex, via interaction with the conserved luminal KASH domain of nesprins (e.g., SYNE1; MIM 608441) located in the outer nuclear membrane (ONM). The LINC complex provides a direct connection between the nuclear lamina and the cytoskeleton, which contributes to nuclear positioning and cellular rigidity (summary by Haque et al., 2010 [PubMed 19933576]).[supplied by OMIM, Nov 2010]

Chromosome

22

Cytoband

q13.1

Chromosome location (bp)

38734725 - 38794143

Protein evidence

Evidence at protein level (all genes)

Ensembl

ENSG00000100242 (version 78.38)

Entrez gene

25777

UniProt

Q9UH99 (UniProt - Evidence at protein level)

neXtProt

NX_Q9UH99

Antibodypedia

SUN2 antibodies
 

PROTEIN VIEW

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SUN2-001
 
SUN2-002
 
SUN2-003
 
SUN2-004
 
SUN2-005
 
SUN2-006
 
SUN2-008
 
SUN2-009
 
SUN2-010
 
SUN2-011
 
SUN2-015
 
SUN2-017
 
 » 
 
 
 
 

PROTEIN INFORMATION

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Splice variant

Ensembl

UniProt

Protein class

Gene ontology

Length
(aa)

Molecular mass
(kDa)

Signal peptide
(predicted)

Transmembrane regions
(predicted)

SUN2-001 ENSP00000385740
ENST00000405510
Q9UH99
Show all »
Show » Show » 717 80.3 No 2
SUN2-002 ENSP00000385616
ENST00000405018
Q9UH99
Show all »
Show » Show » 738 82.5 No 2
SUN2-003 ENSP00000411615
ENST00000433561
B0QY66
Show all »
Show » 110 12.1 No 0
SUN2-004 ENSP00000415588
ENST00000456894
B0QY64
Show all »
Show » 228 25.3 No 2
SUN2-005 ENSP00000414950
ENST00000452294
B0QY67
Show all »
Show » 144 15.7 No 0
SUN2-006 ENSP00000393271
ENST00000439339
B0QY68
Show all »
Show » 101 11.1 No 0
SUN2-008 ENSP00000408834
ENST00000420859
B0QY65
Show all »
Show » 127 13.8 No 0
SUN2-009 ENSP00000406941
ENST00000438058
B0QY63
Show all »
Show » 224 25.4 No 1
SUN2-010 ENSP00000412928
ENST00000417332
B0QY69
Show all »
Show » 124 13.6 No 0
SUN2-011 ENSP00000403694
ENST00000430185
Show » 143 16.5 No 2
SUN2-015 ENSP00000390154
ENST00000455125
B0QY60
Show all »
Show » 198 21.8 No 0
SUN2-017 ENSP00000383992
ENST00000406622
Q9UH99
Show all »
Show » Show » 717 80.3 No 2