DDX17

GENE INFORMATION

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Gene name

DDX17 (HGNC Symbol)

Synonyms

P72

Description

DEAD (Asp-Glu-Ala-Asp) box helicase 17 (HGNC Symbol)

Entrez gene summary

DEAD box proteins, characterized by the conserved motif Asp-Glu-Ala-Asp (DEAD), are putative RNA helicases. They are implicated in a number of cellular processes involving alteration of RNA secondary structure, such as translation initiation, nuclear and mitochondrial splicing, and ribosome and splicesosome assembly. Based on their distribution patterns, some members of this family are believed to be involved in embryogenesis, spermatogenesis, and cellular growth and division. This gene encodes a DEAD box protein, which is an ATPase activated by a variety of RNA species, but not by dsDNA. This protein, and that encoded by DDX5 gene, are more closely related to each other than to any other member of the DEAD box family. This gene can encode multiple isoforms due to both alternative splicing and the use of alternative translation initiation codons, including a non-AUG (CUG) start codon. [provided by RefSeq, Apr 2011]

Chromosome

22

Cytoband

q13.1

Chromosome location (bp)

38483440 - 38507660

Protein evidence

Evidence at protein level (all genes)

Ensembl

ENSG00000100201 (version 78.38)

Entrez gene

10521

UniProt

Q92841 (UniProt - Evidence at protein level)

neXtProt

NX_Q92841

Antibodypedia

DDX17 antibodies
 

PROTEIN VIEW

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DDX17-001
 
DDX17-002
 
 
 
 
 

PROTEIN INFORMATION

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Splice variant

Ensembl

UniProt

Protein class

Gene ontology

Length
(aa)

Molecular mass
(kDa)

Signal peptide
(predicted)

Transmembrane regions
(predicted)

DDX17-001 ENSP00000380033
ENST00000396821
H3BLZ8
Show all »
Show » Show » 731 80.4 Yes 0
DDX17-002 ENSP00000385536
ENST00000403230
Q92841
Show all »
Show » Show » 729 80.3 Yes 0