MED15

GENERAL INFORMATION

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Gene name

MED15

Gene description

Mediator complex subunit 15

Protein class

Predicted intracellular proteins

Predicted localization

Intracellular

Number of transcripts

14
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HUMAN PROTEIN ATLAS INFORMATION

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RNA tissue category

HPA:Expressed in all
GTEx:Expressed in all

Protein evidence

Evidence at protein level

Protein localization

Ubiquitous cytoplasmic and nuclear expression.

ANTIBODY RELIABILITY

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Data reliability
description

Antibody staining mainly consistent with RNA expression data.

Data reliability

Uncertain based on 1 antibody.
HPA003179
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RNA AND PROTEIN EXPRESSION SUMMARY

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RNA expression (FPKM) Protein expression (score)
Brain
Endocrine tissues
Bone marrow & immune system
Muscle tissues
Lung
Liver & gallbladder
Pancreas
Gastrointestinal tract
Kidney & urinary bladder
Male tissues
Female tissues
Adipose & soft tissue
Skin
Cerebral cortex

Lymph node

Liver

Colon

Kidney

Testis

Placenta



PROTEIN EXPRESSION OVERVIEW

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Organ

Expression



RNA EXPRESSION OVERVIEW

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HPA dataset
RNA tissue category:  Expressed in all

Organ

Expression

GTEx dataset
RNA tissue category:  Expressed in all

Organ

Expression



GENE INFORMATION

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Gene name

MED15 (HGNC Symbol)

Synonyms

Arc105, CAG7A, PCQAP, TIG-1, TNRC7

Description

Mediator complex subunit 15 (HGNC Symbol)

Entrez gene summary

The protein encoded by this gene is a subunit of the multiprotein complexes PC2 and ARC/DRIP and may function as a transcriptional coactivator in RNA polymerase II transcription. This gene contains stretches of trinucleotide repeats and is located in the chromosome 22 region which is deleted in DiGeorge syndrome. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jun 2014]

Chromosome

22

Cytoband

q11.21

Chromosome location (bp)

20495913 - 20587632

Protein evidence

Evidence at protein level (all genes)

Ensembl

ENSG00000099917 (version 78.38)

Entrez gene

51586

UniProt

Q96RN5 (UniProt - Evidence at protein level)

neXtProt

NX_Q96RN5

Antibodypedia

MED15 antibodies


PROTEIN BROWSER

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ENST00000263205
 
ENST00000292733
 
ENST00000382974
 
ENST00000406969
 
ENST00000414658
 
ENST00000423862
 
ENST00000424287
 
ENST00000428629
 
ENST00000432052
 
ENST00000438962
 
ENST00000445189
 
ENST00000445987
 
ENST00000451058
 
ENST00000457322
 
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PROTEIN INFORMATION

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Splice variant

Ensembl

UniProt

Protein class

Gene ontology

Length
(aa)

Molecular mass
(kDa)

Signal peptide
(predicted)

Transmembrane regions
(predicted)

MED15-001 ENSP00000292733
ENST00000292733
Q96RN5
Show all »
Show » Show » 748 82.6 No 0
MED15-004 ENSP00000263205
ENST00000263205
Q96RN5
Show all »
Show » Show » 788 86.8 No 0
MED15-005 ENSP00000384344
ENST00000406969
G3V1P5
Show all »
Show » Show » 722 79.6 No 0
MED15-006 ENSP00000372434
ENST00000382974
Q96RN5
Show all »
Show » Show » 677 75.9 No 0
MED15-010 ENSP00000392738
ENST00000414658
C9J1I1
Show all »
Show » Show » 141 14.7 No 0
MED15-011 ENSP00000408794
ENST00000432052
C9JLN7
Show all »
Show » Show » 106 12.3 No 0
MED15-014 ENSP00000410173
ENST00000438962
C9JEM1
Show all »
Show » 119 13 No 0
MED15-015 ENSP00000407742
ENST00000445987
C9JZV5
Show all »
Show » Show » 120 12.3 No 0
MED15-016 ENSP00000390498
ENST00000445189
C9JGN2
Show all »
Show » Show » 124 12.7 No 0
MED15-017 ENSP00000408742
ENST00000451058
C9JM58
Show all »
Show » Show » 105 10.9 No 0
MED15-020 ENSP00000415778
ENST00000457322
C9JJ12
Show all »
Show » Show » 160 17.2 No 0
MED15-021 ENSP00000413603
ENST00000428629
C9JWK5
Show all »
Show » Show » 82 9.6 No 0
MED15-022 ENSP00000396461
ENST00000424287
C9JCQ3
Show all »
Show » Show » 165 17.7 No 0
MED15-023 ENSP00000408875
ENST00000423862
Show » Show » 194 22 No 0