HSP90AB1

GENERAL INFORMATION

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Gene name

HSP90AB1

Gene description

Heat shock protein 90kDa alpha (cytosolic), class B member 1

Protein class

Cancer-related genes
Plasma proteins
Predicted intracellular proteins

Predicted localization

Intracellular

Number of transcripts

4
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HUMAN PROTEIN ATLAS INFORMATION

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RNA tissue category

HPA:Expressed in all
GTEx:Expressed in all

Protein evidence

Evidence at protein level

Protein localization

Ubiquitous cytoplasmic expression.

ANTIBODY RELIABILITY

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Data reliability
description

Antibody staining mainly consistent with RNA expression data.

Data reliability

Uncertain based on 1 antibody.
CAB005230
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RNA AND PROTEIN EXPRESSION SUMMARY

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RNA expression (FPKM) Protein expression (score)
Brain
Endocrine tissues
Bone marrow & immune system
Muscle tissues
Lung
Liver & gallbladder
Pancreas
Gastrointestinal tract
Kidney & urinary bladder
Male tissues
Female tissues
Adipose & soft tissue
Skin
Cerebral cortex

Lymph node

Liver

Colon

Kidney

Testis

Placenta



PROTEIN EXPRESSION OVERVIEW

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Organ

Expression



RNA EXPRESSION OVERVIEW

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HPA dataset
RNA tissue category:  Expressed in all

Organ

Expression

GTEx dataset
RNA tissue category:  Expressed in all

Organ

Expression



GENE INFORMATION

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Gene name

HSP90AB1 (HGNC Symbol)

Synonyms

HSPC2, HSPCB

Description

Heat shock protein 90kDa alpha (cytosolic), class B member 1 (HGNC Symbol)

Entrez gene summary

This gene encodes a member of the heat shock protein 90 family; these proteins are involved in signal transduction, protein folding and degradation and morphological evolution. This gene encodes the constitutive form of the cytosolic 90 kDa heat-shock protein and is thought to play a role in gastric apoptosis and inflammation. Alternative splicing results in multiple transcript variants. Pseudogenes have been identified on multiple chromosomes. [provided by RefSeq, Dec 2012]

Chromosome

6

Cytoband

p21.1

Chromosome location (bp)

44246166 - 44253888

Protein evidence

Evidence at protein level (all genes)

Ensembl

ENSG00000096384 (version 78.38)

Entrez gene

3326

UniProt

P08238 (UniProt - Evidence at protein level)

neXtProt

NX_P08238

Antibodypedia

HSP90AB1 antibodies


PROTEIN BROWSER

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ENST00000353801
 
ENST00000371554
 
ENST00000371646
 
ENST00000620073
 
 
 
 


PROTEIN INFORMATION

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Splice variant

Ensembl

UniProt

Protein class

Gene ontology

Length
(aa)

Molecular mass
(kDa)

Signal peptide
(predicted)

Transmembrane regions
(predicted)

HSP90AB1-003 ENSP00000360709
ENST00000371646
P08238
Show all »
Show » Show » 724 83.3 No 0
HSP90AB1-004 ENSP00000325875
ENST00000353801
P08238
Show all »
Show » Show » 724 83.3 No 0
HSP90AB1-005 ENSP00000360609
ENST00000371554
P08238
Show all »
Show » Show » 724 83.3 No 0
HSP90AB1-201 ENSP00000481908
ENST00000620073
P08238
Show all »
Show » Show » 724 83.3 No 0