TGM1

GENE INFORMATION

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Gene name

TGM1 (HGNC Symbol)

Synonyms

ICR2, LI, LI1, TGASE, TGK

Description

Transglutaminase 1 (HGNC Symbol)

Entrez gene summary

The protein encoded by this gene is a membrane protein that catalyzes the addition of an alkyl group from an akylamine to a glutamine residue of a protein, forming an alkylglutamine in the protein. This protein alkylation leads to crosslinking of proteins and catenation of polyamines to proteins. This gene contains either one or two copies of a 22 nt repeat unit in its 3' UTR. Mutations in this gene have been associated with autosomal recessive lamellar ichthyosis (LI) and nonbullous congenital ichthyosiform erythroderma (NCIE). [provided by RefSeq, Jul 2008]

Chromosome

14

Cytoband

q12

Chromosome location (bp)

24249114 - 24264432

Protein evidence

Evidence at protein level (all genes)

Ensembl

ENSG00000092295 (version 78.38)

Entrez gene

7051

UniProt

P22735 (UniProt - Evidence at protein level)

neXtProt

NX_P22735

Antibodypedia

TGM1 antibodies
 

PROTEIN VIEW

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TGM1-001
 
TGM1-002
 
TGM1-004
 
TGM1-005
 
TGM1-006
 
TGM1-007
 
TGM1-008
 
TGM1-009
 
TGM1-010
 
 
 
 
 

PROTEIN INFORMATION

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Splice variant

Ensembl

UniProt

Protein class

Gene ontology

Length
(aa)

Molecular mass
(kDa)

Signal peptide
(predicted)

Transmembrane regions
(predicted)

TGM1-001 ENSP00000206765
ENST00000206765
P22735
Show all »
Show » Show » 817 89.8 No 0
TGM1-002 ENSP00000439446
ENST00000544573
B4DWR7
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Show » Show » 375 40.6 No 0
TGM1-004 ENSP00000452690
ENST00000561067
Show » 9 1 No 0
TGM1-005 ENSP00000452822
ENST00000560443
H0YKI6
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Show » 65 7 No 0
TGM1-006 ENSP00000453234
ENST00000560478
H0YLJ6
Show all »
Show » 50 5.4 No 0
TGM1-007 ENSP00000454070
ENST00000560226
H0YNM4
Show all »
Show » 42 4.5 No 0
TGM1-008 ENSP00000453840
ENST00000558074
H0YN27
Show all »
Show » 135 14.5 No 0
TGM1-009 ENSP00000453337
ENST00000559136
H0YLT9
Show all »
Show » Show » 209 23.4 No 0
TGM1-010 ENSP00000453701
ENST00000559669
H0YMQ8
Show all »
Show » Show » 128 14 No 0