SUPT16H

GENE INFORMATION

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Gene name

SUPT16H (HGNC Symbol)

Synonyms

CDC68, FACT, FACTP140, FLJ10857, FLJ14010, SPT16/CDC68

Description

Suppressor of Ty 16 homolog (S. cerevisiae) (HGNC Symbol)

Entrez gene summary

Transcription of protein-coding genes can be reconstituted on naked DNA with only the general transcription factors and RNA polymerase II. However, this minimal system cannot transcribe DNA packaged into chromatin, indicating that accessory factors may facilitate access to DNA. One such factor, FACT (facilitates chromatin transcription), interacts specifically with histones H2A/H2B to effect nucleosome disassembly and transcription elongation. FACT is composed of an 80 kDa subunit and a 140 kDa subunit; this gene encodes the 140 kDa subunit. [provided by RefSeq, Feb 2009]

Chromosome

14

Cytoband

q11.2

Chromosome location (bp)

21351472 - 21384266

Protein evidence

Evidence at protein level (all genes)

Ensembl

ENSG00000092201 (version 78.38)

Entrez gene

11198

UniProt

Q9Y5B9 (UniProt - Evidence at protein level)

neXtProt

NX_Q9Y5B9

Antibodypedia

SUPT16H antibodies
 

PROTEIN VIEW

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SUPT16H-001
 
SUPT16H-003
 
 
 
 
 

PROTEIN INFORMATION

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Splice variant

Ensembl

UniProt

Protein class

Gene ontology

Length
(aa)

Molecular mass
(kDa)

Signal peptide
(predicted)

Transmembrane regions
(predicted)

SUPT16H-001 ENSP00000216297
ENST00000216297
Q9Y5B9
Show all »
Show » Show » 1047 119.9 No 0
SUPT16H-003 ENSP00000450910
ENST00000555943
G3V2X0
Show all »
Show » 83 9.8 No 0