SLC26A3

GENE INFORMATION

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Gene name

SLC26A3 (HGNC Symbol)

Synonyms

CLD, DRA

Description

Solute carrier family 26 (anion exchanger), member 3 (HGNC Symbol)

Entrez gene summary

The protein encoded by this gene is a transmembrane glycoprotein that transports chloride ions across the cell membrane in exchange for bicarbonate ions. It is localized to the mucosa of the lower intestinal tract, particularly to the apical membrane of columnar epithelium and some goblet cells. The protein is essential for intestinal chloride absorption, and mutations in this gene have been associated with congenital chloride diarrhea. [provided by RefSeq, Oct 2008]

Chromosome

7

Cytoband

Chromosome location (bp)

107765467 - 107803225

Protein evidence

Evidence at protein level (all genes)

Ensembl

ENSG00000091138 (version 78.38)

Entrez gene

1811

UniProt

P40879 (UniProt - Evidence at protein level)

neXtProt

NX_P40879

Antibodypedia

SLC26A3 antibodies
 

PROTEIN VIEW

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SLC26A3-002
 
SLC26A3-003
 
 
 
 
 

PROTEIN INFORMATION

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Splice variant

Ensembl

UniProt

Protein class

Gene ontology

Length
(aa)

Molecular mass
(kDa)

Signal peptide
(predicted)

Transmembrane regions
(predicted)

SLC26A3-002 ENSP00000345873
ENST00000340010
P40879
Show all »
Show » Show » 764 84.5 No >9
SLC26A3-003 ENSP00000395955
ENST00000453332
C9JFJ2
Show all »
Show » 120 13.5 No 2