TFAP4

GENERAL INFORMATION

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Gene name

TFAP4

Gene description

Transcription factor AP-4 (activating enhancer binding protein 4)

Protein class

Predicted intracellular proteins
Transcription factors

Predicted localization

Intracellular

Number of transcripts

2
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HUMAN PROTEIN ATLAS INFORMATION

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RNA tissue category

HPA:Expressed in all
GTEx:Expressed in all

Protein evidence

Evidence at protein level

Protein localization

Ubiquitous nuclear expression.

ANTIBODY RELIABILITY

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Data reliability
description

Antibody staining mainly consistent with RNA expression data.

Data reliability

Supportive based on 1 antibody.
HPA001912
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RNA AND PROTEIN EXPRESSION SUMMARY

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RNA expression (FPKM) Protein expression (score)
Brain
Endocrine tissues
Bone marrow & immune system
Muscle tissues
Lung
Liver & gallbladder
Pancreas
Gastrointestinal tract
Kidney & urinary bladder
Male tissues
Female tissues
Adipose & soft tissue
Skin
Cerebral cortex

Lymph node

Liver

Colon

Kidney

Testis



PROTEIN EXPRESSION OVERVIEW

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Organ

Expression



RNA EXPRESSION OVERVIEW

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HPA dataset
RNA tissue category:  Expressed in all

Organ

Expression

GTEx dataset
RNA tissue category:  Expressed in all

Organ

Expression



GENE INFORMATION

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Gene name

TFAP4 (HGNC Symbol)

Synonyms

AP-4, bHLHc41

Description

Transcription factor AP-4 (activating enhancer binding protein 4) (HGNC Symbol)

Entrez gene summary

Transcription factors of the basic helix-loop-helix-zipper (bHLH-ZIP) family contain a basic domain, which is used for DNA binding, and HLH and ZIP domains, which are used for oligomerization. Transcription factor AP4 activates both viral and cellular genes by binding to the symmetrical DNA sequence CAGCTG (Mermod et al., 1988 [PubMed 2833704]; Hu et al., 1990 [PubMed 2123466]).[supplied by OMIM, Jul 2009]

Chromosome

16

Cytoband

p13.3

Chromosome location (bp)

4257186 - 4273075

Protein evidence

Evidence at protein level (all genes)

Ensembl

ENSG00000090447 (version 78.38)

Entrez gene

7023

UniProt

Q01664 (UniProt - Evidence at protein level)

neXtProt

NX_Q01664

Antibodypedia

TFAP4 antibodies


PROTEIN BROWSER

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ENST00000204517
 
ENST00000572393
 
 
 
 


PROTEIN INFORMATION

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Splice variant

Ensembl

UniProt

Protein class

Gene ontology

Length
(aa)

Molecular mass
(kDa)

Signal peptide
(predicted)

Transmembrane regions
(predicted)

TFAP4-001 ENSP00000204517
ENST00000204517
Q01664
Show all »
Show » Show » 338 38.7 No 0
TFAP4-007 ENSP00000459390
ENST00000572393
I3L254
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Show » Show » 115 13.5 No 0