MAVS

GENERAL INFORMATION

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Gene name

MAVS

Gene description

Mitochondrial antiviral signaling protein

Protein class

Predicted membrane proteins

Predicted localization

Membrane

Number of transcripts

2
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HUMAN PROTEIN ATLAS INFORMATION

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RNA tissue category

HPA:Expressed in all
GTEx:Expressed in all

Protein evidence

Evidence at protein level

Protein localization

General granular cytoplasmic expression.

ANTIBODY RELIABILITY

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Data reliability
description

Pending RNA-based expert annotation.

Data reliability

Supportive based on 3 antibodies.
HPA049850 , HPA053524 , CAB009187
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RNA AND PROTEIN EXPRESSION SUMMARY

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RNA expression (FPKM) Protein expression (score)
Brain
Endocrine tissues
Bone marrow & immune system
Muscle tissues
Lung
Liver & gallbladder
Pancreas
Gastrointestinal tract
Kidney & urinary bladder
Male tissues
Female tissues
Adipose & soft tissue
Skin
Cerebral cortex

Lymph node

Liver

Colon

Kidney

Testis



PROTEIN EXPRESSION OVERVIEW

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Organ

Expression



RNA EXPRESSION OVERVIEW

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HPA dataset
RNA tissue category:  Expressed in all

Organ

Expression

GTEx dataset
RNA tissue category:  Expressed in all

Organ

Expression



GENE INFORMATION

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Gene name

MAVS (HGNC Symbol)

Synonyms

Cardif, IPS-1, KIAA1271, VISA

Description

Mitochondrial antiviral signaling protein (HGNC Symbol)

Entrez gene summary

This gene encodes an intermediary protein necessary in the virus-triggered beta interferon signaling pathways. It is required for activation of transcription factors which regulate expression of beta interferon and contributes to antiviral immunity. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Sep 2011]

Chromosome

20

Cytoband

p13

Chromosome location (bp)

3846799 - 3876123

Protein evidence

Evidence at protein level (all genes)

Ensembl

ENSG00000088888 (version 78.38)

Entrez gene

57506

UniProt

Q7Z434 (UniProt - Evidence at protein level)

neXtProt

NX_Q7Z434

Antibodypedia

MAVS antibodies


PROTEIN BROWSER

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ENST00000416600
 
ENST00000428216
 
 
 
 


PROTEIN INFORMATION

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Splice variant

Ensembl

UniProt

Protein class

Gene ontology

Length
(aa)

Molecular mass
(kDa)

Signal peptide
(predicted)

Transmembrane regions
(predicted)

MAVS-001 ENSP00000401980
ENST00000428216
Q7Z434
Show all »
Show » Show » 540 56.5 No 1
MAVS-201 ENSP00000413749
ENST00000416600
Q7Z434
Show all »
Show » Show » 399 40.5 No 1