SIGLEC1

GENE INFORMATION

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Gene name

SIGLEC1 (HGNC Symbol)

Synonyms

CD169, dJ1009E24.1, FLJ00051, FLJ00055, FLJ00073, FLJ32150, sialoadhesin, SIGLEC-1, SN

Description

Sialic acid binding Ig-like lectin 1, sialoadhesin (HGNC Symbol)

Entrez gene summary

This gene encodes a member of the immunoglobulin superfamily. The encoded protein is a lectin-like adhesion molecule that binds glycoconjugate ligands on cell surfaces in a sialic acid-dependent manner. It is a type I transmembrane protein expressed only by a subpopulation of macrophages and is involved in mediating cell-cell interactions. Alternative splicing produces a transcript variant encoding an isoform that is soluble rather than membrane-bound; however, the full-length nature of this variant has not been determined. [provided by RefSeq, Jul 2008]

Chromosome

20

Cytoband

p13

Chromosome location (bp)

3686970 - 3707128

Protein evidence

Evidence at protein level (all genes)

Ensembl

ENSG00000088827 (version 78.38)

Entrez gene

6614

UniProt

Q9BZZ2 (UniProt - Evidence at protein level)

neXtProt

NX_Q9BZZ2

Antibodypedia

SIGLEC1 antibodies
 

PROTEIN VIEW

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SIGLEC1-001
 
SIGLEC1-002
 
 
 
 
 

PROTEIN INFORMATION

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Splice variant

Ensembl

UniProt

Protein class

Gene ontology

Length
(aa)

Molecular mass
(kDa)

Signal peptide
(predicted)

Transmembrane regions
(predicted)

SIGLEC1-001 ENSP00000341141
ENST00000344754
Q9BZZ2
Show all »
Show » Show » 1709 182.6 Yes 1
SIGLEC1-002 ENSP00000395778
ENST00000419548
Show » Show » 463 48.4 No 0