Tissue expression of AURKA - Summary - The Human Protein Atlas

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AURKA

TISSUE

SUBCELL

CELL LINE

CANCER

TISSUE ATLAS PRIMARY DATA

GENE/PROTEIN ANTIBODY/ANTIGEN


Dictionary

GENERAL INFORMATION ? »
Protein class Protein class the gene product belongs to according to selected gene lists. List of protein classes. Predicted localization Protein localization predicted from several bioinformatic algorithms. More info... Number of transcripts Number of protein-coding transcribed from this gene as defined by Ensembl.
Gene name	AURKA
Gene description	Aurora kinase A
Protein class	Cancer-related genes Enzymes Plasma proteins Predicted intracellular proteins
Predicted localization	Intracellular
Number of transcripts	13
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HUMAN PROTEIN ATLAS INFORMATION

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RNA tissue category

HPA:	Tissue enhanced (testis)
GTEx:	Tissue enhanced (testis)

Protein evidence

Evidence at protein level

Protein localization

Selective cytoplasmic expression in exocrine pancreas, subsets of lymphoid cells and neuronal cells in CNS.

ANTIBODY RELIABILITY ? »
Data reliability description Standardized explanatory sentences with additional information required for full understanding of the knowledge-based expression profile. Currently, not all genes have been analyzed by knowledge-based annotation, indicated by "Pending RNA-based expert annotation", when applicable. Data reliability Data reliability score (score description), divided into supportive (premium) or uncertain (not premium), is based on consistency between the staining pattern of one antibody or several antibodies with RNA-seq data and available gene/protein characterization data.
Data reliability description	Pending RNA-based expert annotation.
Data reliability	Uncertain based on 2 antibodies. HPA002636 , CAB001454
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RNA AND PROTEIN EXPRESSION SUMMARY

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RNA expression (FPKM)

Protein expression (score)

Brain

Cerebral cortex

Hippocampus

N/A

Lateral ventricle

N/A

Cerebellum

N/A

Endocrine tissues

Thyroid gland

Parathyroid gland

N/A

Adrenal gland

Bone marrow & immune system

Appendix

Bone marrow

Lymph node

Tonsil

Spleen

Muscle tissues

Heart muscle

Skeletal muscle

Smooth muscle

Lung

Nasopharynx

N/A

Bronchus

N/A

Lung

Liver & gallbladder

Liver

Gallbladder

Pancreas

Gastrointestinal tract

Oral mucosa

N/A

Salivary gland

Esophagus

Stomach

Duodenum

Small intestine

Colon

Rectum

Kidney & urinary bladder

Kidney

Urinary bladder

Male tissues

Testis

Epididymis

N/A

Prostate

Seminal vesicle

N/A

Female tissues

Breast

N/A

Vagina

N/A

Cervix, uterine

N/A

Endometrium

Fallopian tube

Ovary

Placenta

Adipose & soft tissue

Adipose tissue

Soft tissue

N/A

Skin

PROTEIN EXPRESSION OVERVIEW

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Organ

Expression

RNA EXPRESSION OVERVIEW

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HPA dataset

RNA tissue category:

Tissue enhanced (testis)

Organ

Expression

GTEx dataset

RNA tissue category:

Tissue enhanced (testis)

Organ

Expression

GENE INFORMATION ? »
Gene information from Ensembl and Entrez, as well as links to available gene identifiers are displayed here. Information was retrieved from Ensembl if not indicated otherwise.
Gene name	AURKA (HGNC Symbol)
Synonyms	AIK, ARK1, AurA, BTAK, PPP1R47, STK15, STK6, STK7
Description	Aurora kinase A (HGNC Symbol)
Entrez gene summary	The protein encoded by this gene is a cell cycle-regulated kinase that appears to be involved in microtubule formation and/or stabilization at the spindle pole during chromosome segregation. The encoded protein is found at the centrosome in interphase cells and at the spindle poles in mitosis. This gene may play a role in tumor development and progression. A processed pseudogene of this gene has been found on chromosome 1, and an unprocessed pseudogene has been found on chromosome 10. Multiple transcript variants encoding the same protein have been found for this gene. [provided by RefSeq, Jul 2008]
Chromosome	20
Cytoband	q13.2
Chromosome location (bp)	56369389 - 56392337
Protein evidence	Evidence at protein level (all genes)
Ensembl	ENSG00000087586 (version 78.38)
Entrez gene	6790
UniProt	O14965 (UniProt - Evidence at protein level)
neXtProt	NX_O14965
Antibodypedia	AURKA antibodies

PROTEIN BROWSER

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ENST00000312783		ENST00000347343		ENST00000371356		ENST00000395907		ENST00000395911		ENST00000395913		ENST00000395914		ENST00000395915		ENST00000420474		ENST00000422322		ENST00000441357		ENST00000451915		ENST00000456249

PROTEIN INFORMATION

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Splice variant	Ensembl	UniProt	Protein class	Gene ontology	Length (aa)	Molecular mass (kDa)	Signal peptide (predicted)
AURKA-001	ENSP00000216911 ENST00000347343	O14965 Show all » « Hide O14965 [Direct mapping] Aurora kinase A Q5QPD4 [Target identity:67%; Query identity:100%] Aurora kinase A {ECO:0000313\|Ensembl:ENSP00000393452} A3KFJ1 [Target identity:46%; Query identity:100%] Aurora kinase A {ECO:0000313\|Ensembl:ENSP00000388073} Q5QPD2 [Target identity:36%; Query identity:100%] Aurora kinase A {ECO:0000313\|Ensembl:ENSP00000405042} Q5QPD1 [Target identity:26%; Query identity:100%] Aurora kinase A {ECO:0000313\|Ensembl:ENSP00000405170} A3KFJ2 [Target identity:19%; Query identity:100%] Aurora kinase A {ECO:0000313\|Ensembl:ENSP00000401358}	Show » « Hide Enzymes ENZYME proteins Transferases Kinases MEMSAT-SVM predicted membrane proteins SPOCTOPUS predicted membrane proteins Predicted intracellular proteins Plasma proteins Cancer-related genes Candidate cancer biomarkers Protein evidence (Kim et al 2014) Protein evidence (Ezkurdia et al 2014)	Show » « Hide GO:0000086 [G2/M transition of mitotic cell cycle] GO:0000212 [meiotic spindle organization] GO:0000226 [microtubule cytoskeleton organization] GO:0000278 [mitotic cell cycle] GO:0004672 [protein kinase activity] GO:0004674 [protein serine/threonine kinase activity] GO:0004712 [protein serine/threonine/tyrosine kinase activity] GO:0004713 [protein tyrosine kinase activity] GO:0005515 [protein binding] GO:0005524 [ATP binding] GO:0005634 [nucleus] GO:0005813 [centrosome] GO:0005815 [microtubule organizing center] GO:0005819 [spindle] GO:0005829 [cytosol] GO:0005876 [spindle microtubule] GO:0006468 [protein phosphorylation] GO:0007052 [mitotic spindle organization] GO:0007057 [spindle assembly involved in female meiosis I] GO:0007067 [mitotic nuclear division] GO:0007100 [mitotic centrosome separation] GO:0007126 [meiotic nuclear division] GO:0009948 [anterior/posterior axis specification] GO:0015630 [microtubule cytoskeleton] GO:0016772 [transferase activity, transferring phosphorus-containing groups] GO:0019901 [protein kinase binding] GO:0030496 [midbody] GO:0031145 [anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process] GO:0031616 [spindle pole centrosome] GO:0031625 [ubiquitin protein ligase binding] GO:0031647 [regulation of protein stability] GO:0032091 [negative regulation of protein binding] GO:0032436 [positive regulation of proteasomal ubiquitin-dependent protein catabolic process] GO:0035174 [histone serine kinase activity] GO:0035404 [histone-serine phosphorylation] GO:0042585 [germinal vesicle] GO:0043066 [negative regulation of apoptotic process] GO:0043146 [spindle stabilization] GO:0043203 [axon hillock] GO:0045120 [pronucleus] GO:0045840 [positive regulation of mitosis] GO:0046605 [regulation of centrosome cycle] GO:0046777 [protein autophosphorylation] GO:0048471 [perinuclear region of cytoplasm] GO:0051297 [centrosome organization] GO:0051642 [centrosome localization] GO:0071539 [protein localization to centrosome] GO:0072686 [mitotic spindle] GO:0072687 [meiotic spindle] GO:0090233 [negative regulation of spindle checkpoint] GO:1900195 [positive regulation of oocyte maturation] GO:1990138 [neuron projection extension]	403	45.8	No
AURKA-002	ENSP00000393452 ENST00000441357	Q5QPD4 Show all » « Hide Q5QPD4 [Target identity:100%; Query identity:100%] Aurora kinase A {ECO:0000313\|Ensembl:ENSP00000393452} A3KFJ1 [Target identity:69%; Query identity:100%] Aurora kinase A {ECO:0000313\|Ensembl:ENSP00000388073} Q5QPD2 [Target identity:53%; Query identity:100%] Aurora kinase A {ECO:0000313\|Ensembl:ENSP00000405042} Q5QPD1 [Target identity:39%; Query identity:100%] Aurora kinase A {ECO:0000313\|Ensembl:ENSP00000405170} A3KFJ2 [Target identity:29%; Query identity:100%] Aurora kinase A {ECO:0000313\|Ensembl:ENSP00000401358}	Show » « Hide Predicted intracellular proteins Protein evidence (Kim et al 2014) Protein evidence (Ezkurdia et al 2014)	Show » « Hide GO:0004672 [protein kinase activity] GO:0004713 [protein tyrosine kinase activity] GO:0005524 [ATP binding] GO:0006468 [protein phosphorylation] GO:0016772 [transferase activity, transferring phosphorus-containing groups]	271	30.7	No
AURKA-003	ENSP00000379251 ENST00000395915	O14965 Show all » « Hide O14965 [Direct mapping] Aurora kinase A Q5QPD4 [Target identity:67%; Query identity:100%] Aurora kinase A {ECO:0000313\|Ensembl:ENSP00000393452} A3KFJ1 [Target identity:46%; Query identity:100%] Aurora kinase A {ECO:0000313\|Ensembl:ENSP00000388073} Q5QPD2 [Target identity:36%; Query identity:100%] Aurora kinase A {ECO:0000313\|Ensembl:ENSP00000405042} Q5QPD1 [Target identity:26%; Query identity:100%] Aurora kinase A {ECO:0000313\|Ensembl:ENSP00000405170} A3KFJ2 [Target identity:19%; Query identity:100%] Aurora kinase A {ECO:0000313\|Ensembl:ENSP00000401358}	Show » « Hide Enzymes ENZYME proteins Transferases Kinases MEMSAT-SVM predicted membrane proteins SPOCTOPUS predicted membrane proteins Predicted intracellular proteins Plasma proteins Cancer-related genes Candidate cancer biomarkers Protein evidence (Kim et al 2014) Protein evidence (Ezkurdia et al 2014)	Show » « Hide GO:0000086 [G2/M transition of mitotic cell cycle] GO:0000278 [mitotic cell cycle] GO:0004672 [protein kinase activity] GO:0004674 [protein serine/threonine kinase activity] GO:0004712 [protein serine/threonine/tyrosine kinase activity] GO:0004713 [protein tyrosine kinase activity] GO:0005515 [protein binding] GO:0005524 [ATP binding] GO:0005634 [nucleus] GO:0005813 [centrosome] GO:0005819 [spindle] GO:0005829 [cytosol] GO:0005876 [spindle microtubule] GO:0006468 [protein phosphorylation] GO:0007067 [mitotic nuclear division] GO:0015630 [microtubule cytoskeleton] GO:0016772 [transferase activity, transferring phosphorus-containing groups] GO:0019901 [protein kinase binding] GO:0030496 [midbody] GO:0031145 [anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process] GO:0031616 [spindle pole centrosome] GO:0031647 [regulation of protein stability] GO:0032091 [negative regulation of protein binding] GO:0043146 [spindle stabilization] GO:0045840 [positive regulation of mitosis] GO:0046605 [regulation of centrosome cycle] GO:0046777 [protein autophosphorylation] GO:0048471 [perinuclear region of cytoplasm]	403	45.8	No
AURKA-004	ENSP00000321591 ENST00000312783	O14965 Show all » « Hide O14965 [Direct mapping] Aurora kinase A Q5QPD4 [Target identity:67%; Query identity:100%] Aurora kinase A {ECO:0000313\|Ensembl:ENSP00000393452} A3KFJ1 [Target identity:46%; Query identity:100%] Aurora kinase A {ECO:0000313\|Ensembl:ENSP00000388073} Q5QPD2 [Target identity:36%; Query identity:100%] Aurora kinase A {ECO:0000313\|Ensembl:ENSP00000405042} Q5QPD1 [Target identity:26%; Query identity:100%] Aurora kinase A {ECO:0000313\|Ensembl:ENSP00000405170} A3KFJ2 [Target identity:19%; Query identity:100%] Aurora kinase A {ECO:0000313\|Ensembl:ENSP00000401358}	Show » « Hide Enzymes ENZYME proteins Transferases Kinases MEMSAT-SVM predicted membrane proteins SPOCTOPUS predicted membrane proteins Predicted intracellular proteins Plasma proteins Cancer-related genes Candidate cancer biomarkers Protein evidence (Kim et al 2014) Protein evidence (Ezkurdia et al 2014)	Show » « Hide GO:0000086 [G2/M transition of mitotic cell cycle] GO:0000278 [mitotic cell cycle] GO:0004672 [protein kinase activity] GO:0004674 [protein serine/threonine kinase activity] GO:0004712 [protein serine/threonine/tyrosine kinase activity] GO:0004713 [protein tyrosine kinase activity] GO:0005515 [protein binding] GO:0005524 [ATP binding] GO:0005634 [nucleus] GO:0005813 [centrosome] GO:0005819 [spindle] GO:0005829 [cytosol] GO:0005876 [spindle microtubule] GO:0006468 [protein phosphorylation] GO:0007067 [mitotic nuclear division] GO:0015630 [microtubule cytoskeleton] GO:0016772 [transferase activity, transferring phosphorus-containing groups] GO:0019901 [protein kinase binding] GO:0030496 [midbody] GO:0031145 [anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process] GO:0031616 [spindle pole centrosome] GO:0031647 [regulation of protein stability] GO:0032091 [negative regulation of protein binding] GO:0043146 [spindle stabilization] GO:0045840 [positive regulation of mitosis] GO:0046605 [regulation of centrosome cycle] GO:0046777 [protein autophosphorylation] GO:0048471 [perinuclear region of cytoplasm]	403	45.8	No
AURKA-005	ENSP00000360407 ENST00000371356	O14965 Show all » « Hide O14965 [Direct mapping] Aurora kinase A Q5QPD4 [Target identity:67%; Query identity:100%] Aurora kinase A {ECO:0000313\|Ensembl:ENSP00000393452} A3KFJ1 [Target identity:46%; Query identity:100%] Aurora kinase A {ECO:0000313\|Ensembl:ENSP00000388073} Q5QPD2 [Target identity:36%; Query identity:100%] Aurora kinase A {ECO:0000313\|Ensembl:ENSP00000405042} Q5QPD1 [Target identity:26%; Query identity:100%] Aurora kinase A {ECO:0000313\|Ensembl:ENSP00000405170} A3KFJ2 [Target identity:19%; Query identity:100%] Aurora kinase A {ECO:0000313\|Ensembl:ENSP00000401358}	Show » « Hide Enzymes ENZYME proteins Transferases Kinases MEMSAT-SVM predicted membrane proteins SPOCTOPUS predicted membrane proteins Predicted intracellular proteins Plasma proteins Cancer-related genes Candidate cancer biomarkers Protein evidence (Kim et al 2014) Protein evidence (Ezkurdia et al 2014)	Show » « Hide GO:0000086 [G2/M transition of mitotic cell cycle] GO:0000278 [mitotic cell cycle] GO:0004672 [protein kinase activity] GO:0004674 [protein serine/threonine kinase activity] GO:0004712 [protein serine/threonine/tyrosine kinase activity] GO:0004713 [protein tyrosine kinase activity] GO:0005515 [protein binding] GO:0005524 [ATP binding] GO:0005634 [nucleus] GO:0005813 [centrosome] GO:0005819 [spindle] GO:0005829 [cytosol] GO:0005876 [spindle microtubule] GO:0006468 [protein phosphorylation] GO:0007067 [mitotic nuclear division] GO:0015630 [microtubule cytoskeleton] GO:0016772 [transferase activity, transferring phosphorus-containing groups] GO:0019901 [protein kinase binding] GO:0030496 [midbody] GO:0031145 [anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process] GO:0031616 [spindle pole centrosome] GO:0031647 [regulation of protein stability] GO:0032091 [negative regulation of protein binding] GO:0043146 [spindle stabilization] GO:0045840 [positive regulation of mitosis] GO:0046605 [regulation of centrosome cycle] GO:0046777 [protein autophosphorylation] GO:0048471 [perinuclear region of cytoplasm]	403	45.8	No
AURKA-006	ENSP00000379249 ENST00000395913	O14965 Show all » « Hide O14965 [Direct mapping] Aurora kinase A Q5QPD4 [Target identity:67%; Query identity:100%] Aurora kinase A {ECO:0000313\|Ensembl:ENSP00000393452} A3KFJ1 [Target identity:46%; Query identity:100%] Aurora kinase A {ECO:0000313\|Ensembl:ENSP00000388073} Q5QPD2 [Target identity:36%; Query identity:100%] Aurora kinase A {ECO:0000313\|Ensembl:ENSP00000405042} Q5QPD1 [Target identity:26%; Query identity:100%] Aurora kinase A {ECO:0000313\|Ensembl:ENSP00000405170} A3KFJ2 [Target identity:19%; Query identity:100%] Aurora kinase A {ECO:0000313\|Ensembl:ENSP00000401358}	Show » « Hide Enzymes ENZYME proteins Transferases Kinases MEMSAT-SVM predicted membrane proteins SPOCTOPUS predicted membrane proteins Predicted intracellular proteins Plasma proteins Cancer-related genes Candidate cancer biomarkers Protein evidence (Kim et al 2014) Protein evidence (Ezkurdia et al 2014)	Show » « Hide GO:0000086 [G2/M transition of mitotic cell cycle] GO:0000278 [mitotic cell cycle] GO:0004672 [protein kinase activity] GO:0004674 [protein serine/threonine kinase activity] GO:0004712 [protein serine/threonine/tyrosine kinase activity] GO:0004713 [protein tyrosine kinase activity] GO:0005515 [protein binding] GO:0005524 [ATP binding] GO:0005634 [nucleus] GO:0005813 [centrosome] GO:0005819 [spindle] GO:0005829 [cytosol] GO:0005876 [spindle microtubule] GO:0006468 [protein phosphorylation] GO:0007067 [mitotic nuclear division] GO:0015630 [microtubule cytoskeleton] GO:0016772 [transferase activity, transferring phosphorus-containing groups] GO:0019901 [protein kinase binding] GO:0030496 [midbody] GO:0031145 [anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process] GO:0031616 [spindle pole centrosome] GO:0031647 [regulation of protein stability] GO:0032091 [negative regulation of protein binding] GO:0043146 [spindle stabilization] GO:0045840 [positive regulation of mitosis] GO:0046605 [regulation of centrosome cycle] GO:0046777 [protein autophosphorylation] GO:0048471 [perinuclear region of cytoplasm]	403	45.8	No
AURKA-007	ENSP00000405170 ENST00000456249	Q5QPD1 Show all » « Hide Q5QPD1 [Target identity:100%; Query identity:100%] Aurora kinase A {ECO:0000313\|Ensembl:ENSP00000405170} A3KFJ2 [Target identity:74%; Query identity:100%] Aurora kinase A {ECO:0000313\|Ensembl:ENSP00000401358}	Show » « Hide Predicted intracellular proteins Protein evidence (Kim et al 2014) Protein evidence (Ezkurdia et al 2014)		106	11.5	No
AURKA-008	ENSP00000405042 ENST00000422322	Q5QPD2 Show all » « Hide Q5QPD2 [Target identity:99%; Query identity:100%] Aurora kinase A {ECO:0000313\|Ensembl:ENSP00000405042} Q5QPD1 [Target identity:72%; Query identity:100%] Aurora kinase A {ECO:0000313\|Ensembl:ENSP00000405170} A3KFJ2 [Target identity:53%; Query identity:100%] Aurora kinase A {ECO:0000313\|Ensembl:ENSP00000401358}	Show » « Hide Predicted intracellular proteins Protein evidence (Kim et al 2014) Protein evidence (Ezkurdia et al 2014)	Show » « Hide GO:0016772 [transferase activity, transferring phosphorus-containing groups]	147	16.2	No
AURKA-009	ENSP00000388073 ENST00000420474	A3KFJ1 Show all » « Hide A3KFJ1 [Target identity:99%; Query identity:100%] Aurora kinase A {ECO:0000313\|Ensembl:ENSP00000388073} Q5QPD2 [Target identity:77%; Query identity:100%] Aurora kinase A {ECO:0000313\|Ensembl:ENSP00000405042} Q5QPD1 [Target identity:56%; Query identity:100%] Aurora kinase A {ECO:0000313\|Ensembl:ENSP00000405170} A3KFJ2 [Target identity:41%; Query identity:100%] Aurora kinase A {ECO:0000313\|Ensembl:ENSP00000401358}	Show » « Hide Predicted intracellular proteins Protein evidence (Kim et al 2014) Protein evidence (Ezkurdia et al 2014)	Show » « Hide GO:0004672 [protein kinase activity] GO:0005524 [ATP binding] GO:0006468 [protein phosphorylation] GO:0016772 [transferase activity, transferring phosphorus-containing groups]	189	21.2	No
AURKA-010	ENSP00000379247 ENST00000395911	O14965 Show all » « Hide O14965 [Direct mapping] Aurora kinase A Q5QPD4 [Target identity:67%; Query identity:100%] Aurora kinase A {ECO:0000313\|Ensembl:ENSP00000393452} A3KFJ1 [Target identity:46%; Query identity:100%] Aurora kinase A {ECO:0000313\|Ensembl:ENSP00000388073} Q5QPD2 [Target identity:36%; Query identity:100%] Aurora kinase A {ECO:0000313\|Ensembl:ENSP00000405042} Q5QPD1 [Target identity:26%; Query identity:100%] Aurora kinase A {ECO:0000313\|Ensembl:ENSP00000405170} A3KFJ2 [Target identity:19%; Query identity:100%] Aurora kinase A {ECO:0000313\|Ensembl:ENSP00000401358}	Show » « Hide Enzymes ENZYME proteins Transferases Kinases MEMSAT-SVM predicted membrane proteins SPOCTOPUS predicted membrane proteins Predicted intracellular proteins Plasma proteins Cancer-related genes Candidate cancer biomarkers Protein evidence (Kim et al 2014) Protein evidence (Ezkurdia et al 2014)	Show » « Hide GO:0000086 [G2/M transition of mitotic cell cycle] GO:0000278 [mitotic cell cycle] GO:0004672 [protein kinase activity] GO:0004674 [protein serine/threonine kinase activity] GO:0004712 [protein serine/threonine/tyrosine kinase activity] GO:0004713 [protein tyrosine kinase activity] GO:0005515 [protein binding] GO:0005524 [ATP binding] GO:0005634 [nucleus] GO:0005813 [centrosome] GO:0005819 [spindle] GO:0005829 [cytosol] GO:0005876 [spindle microtubule] GO:0006468 [protein phosphorylation] GO:0007067 [mitotic nuclear division] GO:0015630 [microtubule cytoskeleton] GO:0016772 [transferase activity, transferring phosphorus-containing groups] GO:0019901 [protein kinase binding] GO:0030496 [midbody] GO:0031145 [anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process] GO:0031616 [spindle pole centrosome] GO:0031647 [regulation of protein stability] GO:0032091 [negative regulation of protein binding] GO:0043146 [spindle stabilization] GO:0045840 [positive regulation of mitosis] GO:0046605 [regulation of centrosome cycle] GO:0046777 [protein autophosphorylation] GO:0048471 [perinuclear region of cytoplasm]	403	45.8	No
AURKA-011	ENSP00000379243 ENST00000395907	A3KFJ0 Show all » « Hide A3KFJ0 [Target identity:100%; Query identity:100%] Aurora kinase A {ECO:0000313\|Ensembl:ENSP00000379243} Q5QPD4 [Target identity:78%; Query identity:100%] Aurora kinase A {ECO:0000313\|Ensembl:ENSP00000393452} A3KFJ1 [Target identity:54%; Query identity:100%] Aurora kinase A {ECO:0000313\|Ensembl:ENSP00000388073} Q5QPD2 [Target identity:42%; Query identity:100%] Aurora kinase A {ECO:0000313\|Ensembl:ENSP00000405042} Q5QPD1 [Target identity:30%; Query identity:100%] Aurora kinase A {ECO:0000313\|Ensembl:ENSP00000405170} A3KFJ2 [Target identity:22%; Query identity:100%] Aurora kinase A {ECO:0000313\|Ensembl:ENSP00000401358}	Show » « Hide MEMSAT-SVM predicted membrane proteins SPOCTOPUS predicted membrane proteins Predicted intracellular proteins Protein evidence (Kim et al 2014) Protein evidence (Ezkurdia et al 2014)	Show » « Hide GO:0004672 [protein kinase activity] GO:0004674 [protein serine/threonine kinase activity] GO:0004713 [protein tyrosine kinase activity] GO:0005524 [ATP binding] GO:0006468 [protein phosphorylation] GO:0016772 [transferase activity, transferring phosphorus-containing groups]	347	39.5	No
AURKA-012	ENSP00000401358 ENST00000451915	A3KFJ2 Show all » « Hide A3KFJ2 [Target identity:100%; Query identity:100%] Aurora kinase A {ECO:0000313\|Ensembl:ENSP00000401358}	Show » « Hide Predicted intracellular proteins Protein evidence (Kim et al 2014) Protein evidence (Ezkurdia et al 2014)		79	8.6	No
AURKA-201	ENSP00000379250 ENST00000395914	O14965 Show all » « Hide O14965 [Direct mapping] Aurora kinase A Q5QPD4 [Target identity:67%; Query identity:100%] Aurora kinase A {ECO:0000313\|Ensembl:ENSP00000393452} A3KFJ1 [Target identity:46%; Query identity:100%] Aurora kinase A {ECO:0000313\|Ensembl:ENSP00000388073} Q5QPD2 [Target identity:36%; Query identity:100%] Aurora kinase A {ECO:0000313\|Ensembl:ENSP00000405042} Q5QPD1 [Target identity:26%; Query identity:100%] Aurora kinase A {ECO:0000313\|Ensembl:ENSP00000405170} A3KFJ2 [Target identity:19%; Query identity:100%] Aurora kinase A {ECO:0000313\|Ensembl:ENSP00000401358}	Show » « Hide Enzymes ENZYME proteins Transferases Kinases MEMSAT-SVM predicted membrane proteins SPOCTOPUS predicted membrane proteins Predicted intracellular proteins Plasma proteins Cancer-related genes Candidate cancer biomarkers Protein evidence (Kim et al 2014) Protein evidence (Ezkurdia et al 2014)	Show » « Hide GO:0000086 [G2/M transition of mitotic cell cycle] GO:0000278 [mitotic cell cycle] GO:0004672 [protein kinase activity] GO:0004674 [protein serine/threonine kinase activity] GO:0004712 [protein serine/threonine/tyrosine kinase activity] GO:0004713 [protein tyrosine kinase activity] GO:0005515 [protein binding] GO:0005524 [ATP binding] GO:0005634 [nucleus] GO:0005813 [centrosome] GO:0005819 [spindle] GO:0005829 [cytosol] GO:0005876 [spindle microtubule] GO:0006468 [protein phosphorylation] GO:0007067 [mitotic nuclear division] GO:0015630 [microtubule cytoskeleton] GO:0016772 [transferase activity, transferring phosphorus-containing groups] GO:0019901 [protein kinase binding] GO:0030496 [midbody] GO:0031145 [anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process] GO:0031616 [spindle pole centrosome] GO:0031647 [regulation of protein stability] GO:0032091 [negative regulation of protein binding] GO:0043146 [spindle stabilization] GO:0045840 [positive regulation of mitosis] GO:0046605 [regulation of centrosome cycle] GO:0046777 [protein autophosphorylation] GO:0048471 [perinuclear region of cytoplasm]	403	45.8	No

The Human Protein Atlas project is funded by the Knut & Alice Wallenberg foundation.

Protein class

Predicted localization

Number of transcripts

RNA tissue category

Protein evidence

Protein localization

Data reliability description

Data reliability

RNA expression (FPKM)

Protein expression (score)

HPA dataset

RNA tissue category HPA

GTEx dataset

RNA tissue category GTEx