TFAP2C

GENERAL INFORMATION

? »

Gene name

TFAP2C

Gene description

Transcription factor AP-2 gamma (activating enhancer binding protein 2 gamma)

Protein class

Predicted intracellular proteins
Transcription factors

Predicted localization

Intracellular

Number of transcripts

2
SHOW MORE

HUMAN PROTEIN ATLAS INFORMATION

? »

RNA tissue category

HPA:Tissue enhanced (skin)
GTEx:Tissue enhanced (skin)

Protein evidence

Evidence at protein level

Protein localization

Nuclear expression in a subset of tissues including skin, placenta and breast.

ANTIBODY RELIABILITY

? »

Data reliability
description

Antibody staining mainly consistent with RNA expression data.

Data reliability

Supportive based on 3 antibodies.
HPA055179 , CAB016061 , CAB016079
SHOW MORE

RNA AND PROTEIN EXPRESSION SUMMARY

? »
RNA expression (FPKM) Protein expression (score)
Brain
Endocrine tissues
Bone marrow & immune system
Muscle tissues
Lung
Liver & gallbladder
Pancreas
Gastrointestinal tract
Kidney & urinary bladder
Male tissues
Female tissues
Adipose & soft tissue
Skin
Cerebral cortex

Lymph node

Liver

Colon

Kidney

Testis

Skin



PROTEIN EXPRESSION OVERVIEW

? »

Organ

Expression



RNA EXPRESSION OVERVIEW

? »
HPA dataset
RNA tissue category:  Tissue enhanced (skin)

Organ

Expression

GTEx dataset
RNA tissue category:  Tissue enhanced (skin)

Organ

Expression



GENE INFORMATION

? »

Gene name

TFAP2C (HGNC Symbol)

Synonyms

AP2-GAMMA, ERF1, hAP-2g, TFAP2G

Description

Transcription factor AP-2 gamma (activating enhancer binding protein 2 gamma) (HGNC Symbol)

Entrez gene summary

The protein encoded by this gene is a sequence-specific DNA-binding transcription factor involved in the activation of several developmental genes. The encoded protein can act as either a homodimer or heterodimer with other family members and is induced during retinoic acid-mediated differentiation. It plays a role in the development of the eyes, face, body wall, limbs, and neural tube. [provided by RefSeq, Jul 2008]

Chromosome

20

Cytoband

q13.31

Chromosome location (bp)

56629302 - 56639283

Protein evidence

Evidence at protein level (all genes)

Ensembl

ENSG00000087510 (version 78.38)

Entrez gene

7022

UniProt

Q92754 (UniProt - Evidence at protein level)

neXtProt

NX_Q92754

Antibodypedia

TFAP2C antibodies


PROTEIN BROWSER

? »
 
 
 
ENST00000201031
 
ENST00000416606
 
 
 
 


PROTEIN INFORMATION

? »

Splice variant

Ensembl

UniProt

Protein class

Gene ontology

Length
(aa)

Molecular mass
(kDa)

Signal peptide
(predicted)

Transmembrane regions
(predicted)

TFAP2C-001 ENSP00000201031
ENST00000201031
Q92754
Show all »
Show » Show » 450 49.2 No 0
TFAP2C-002 ENSP00000390857
ENST00000416606
A2A2R7
Show all »
Show » Show » 118 12.6 No 0