FAT2

GENE INFORMATION

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Gene name

FAT2 (HGNC Symbol)

Synonyms

CDHF8, CDHR9, HFAT2, MEGF1

Description

FAT atypical cadherin 2 (HGNC Symbol)

Entrez gene summary

This gene is the second identified human homolog of the Drosophila fat gene, which encodes a tumor suppressor essential for controlling cell proliferation during Drosophila development. The gene product is a member of the cadherin superfamily, a group of integral membrane proteins characterized by the presence of cadherin-type repeats. In addition to containing 34 tandem cadherin-type repeats, the gene product has two epidermal growth factor (EGF)-like repeats and one laminin G domain. This protein most likely functions as a cell adhesion molecule, controlling cell proliferation and playing an important role in cerebellum development. [provided by RefSeq, Jul 2008]

Chromosome

5

Cytoband

q33.1

Chromosome location (bp)

151504093 - 151568944

Protein evidence

Evidence at protein level (all genes)

Ensembl

ENSG00000086570 (version 78.38)

Entrez gene

2196

UniProt

Q9NYQ8 (UniProt - Evidence at protein level)

neXtProt

NX_Q9NYQ8

Antibodypedia

FAT2 antibodies
 

PROTEIN VIEW

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FAT2-001
 
FAT2-002
 
 
 
 
 

PROTEIN INFORMATION

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Splice variant

Ensembl

UniProt

Protein class

Gene ontology

Length
(aa)

Molecular mass
(kDa)

Signal peptide
(predicted)

Transmembrane regions
(predicted)

FAT2-001 ENSP00000261800
ENST00000261800
Q9NYQ8
Show all »
Show » Show » 4349 479.3 Yes 1
FAT2-002 ENSP00000429678
ENST00000520200
Show » Show » 1122 122.2 No 1