ERC1

GENE INFORMATION

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Gene name

ERC1 (HGNC Symbol)

Synonyms

CAST2, ELKS, KIAA1081, MGC12974, RAB6IP2

Description

ELKS/RAB6-interacting/CAST family member 1 (HGNC Symbol)

Entrez gene summary

The protein encoded by this gene is a member of a family of RIM-binding proteins. RIMs are active zone proteins that regulate neurotransmitter release. This gene has been found fused to the receptor-type tyrosine kinase gene RET by gene rearrangement due to the translocation t(10;12)(q11;p13) in thyroid papillary carcinoma. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jul 2014]

Chromosome

12

Cytoband

p13.33

Chromosome location (bp)

990509 - 1495933

Protein evidence

Evidence at protein level (all genes)

Ensembl

ENSG00000082805 (version 78.38)

Entrez gene

23085

UniProt

Q8IUD2 (UniProt - Evidence at protein level)

neXtProt

NX_Q8IUD2

Antibodypedia

ERC1 antibodies
 

PROTEIN VIEW

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 « 
 
ERC1-001
 
ERC1-005
 
ERC1-006
 
ERC1-011
 
ERC1-014
 
ERC1-015
 
ERC1-020
 
ERC1-023
 
ERC1-201
 
ERC1-202
 
ERC1-203
 
 » 
 
 
 
 

PROTEIN INFORMATION

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Splice variant

Ensembl

UniProt

Protein class

Gene ontology

Length
(aa)

Molecular mass
(kDa)

Signal peptide
(predicted)

Transmembrane regions
(predicted)

ERC1-001 ENSP00000438546
ENST00000543086
Q8IUD2
Show all »
Show » Show » 1088 124.9 No 0
ERC1-005 ENSP00000465628
ENST00000545318
K7EKH8
Show all »
Show » 90 9.3 No 0
ERC1-006 ENSP00000467476
ENST00000592048
K7EPP6
Show all »
Show » 344 40.6 No 0
ERC1-011 ENSP00000347621
ENST00000355446
G8JLD3
Show all »
Show » 1086 124.8 No 0
ERC1-014 ENSP00000354158
ENST00000360905
Q8IUD2
Show all »
Show » Show » 1116 128.1 No 0
ERC1-015 ENSP00000442739
ENST00000546231
X6RLX0
Show all »
Show » 1120 128.5 No 0
ERC1-020 ENSP00000467196
ENST00000539802
Show » 89 10.1 No 0
ERC1-023 ENSP00000464959
ENST00000589132
K7EIZ7
Show all »
Show » 145 14.9 No 0
ERC1-201 ENSP00000380386
ENST00000397203
Q8IUD2
Show all »
Show » Show » 1088 124.9 No 0
ERC1-202 ENSP00000468263
ENST00000589028
Q8IUD2
Show all »
Show » Show » 1116 128.1 No 0
ERC1-203 ENSP00000479523
ENST00000611180
Q8IUD2
Show all »
Show » Show » 720 82 No 0