ATP8B1

GENE INFORMATION

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Gene name

ATP8B1 (HGNC Symbol)

Synonyms

ATPIC, BRIC, FIC1, PFIC, PFIC1

Description

ATPase, aminophospholipid transporter, class I, type 8B, member 1 (HGNC Symbol)

Entrez gene summary

This gene encodes a member of the P-type cation transport ATPase family, which belongs to the subfamily of aminophospholipid-transporting ATPases. The aminophospholipid translocases transport phosphatidylserine and phosphatidylethanolamine from one side of a bilayer to another. Mutations in this gene may result in progressive familial intrahepatic cholestasis type 1 and in benign recurrent intrahepatic cholestasis. [provided by RefSeq, Jul 2008]

Chromosome

18

Cytoband

q21.31

Chromosome location (bp)

57646426 - 57803101

Protein evidence

Evidence at protein level (all genes)

Ensembl

ENSG00000081923 (version 78.38)

Entrez gene

5205

UniProt

O43520 (UniProt - Evidence at protein level)

neXtProt

NX_O43520

Antibodypedia

ATP8B1 antibodies
 

PROTEIN VIEW

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ATP8B1-001
 
ATP8B1-003
 
ATP8B1-006
 
ATP8B1-201
 
 
 
 
 

PROTEIN INFORMATION

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Splice variant

Ensembl

UniProt

Protein class

Gene ontology

Length
(aa)

Molecular mass
(kDa)

Signal peptide
(predicted)

Transmembrane regions
(predicted)

ATP8B1-001 ENSP00000283684
ENST00000283684
O43520
Show all »
Show » Show » 1251 143.7 No >9
ATP8B1-003 ENSP00000468266
ENST00000588255
K7ERI0
Show all »
Show » Show » 92 10.8 No 0
ATP8B1-006 ENSP00000468751
ENST00000585322
Show » 11 1.3 No 0
ATP8B1-201 ENSP00000445359
ENST00000536015
O43520
Show all »
Show » Show » 1251 143.7 No >9