COL5A3

GENE INFORMATION

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Gene name

COL5A3

Synonyms

Description

Collagen, type V, alpha 3 (HGNC Symbol)

Entrez gene summary

This gene encodes an alpha chain for one of the low abundance fibrillar collagens. Fibrillar collagen molecules are trimers that can be composed of one or more types of alpha chains. Type V collagen is found in tissues containing type I collagen and appears to regulate the assembly of heterotypic fibers composed of both type I and type V collagen. This gene product is closely related to type XI collagen and it is possible that the collagen chains of types V and XI constitute a single collagen type with tissue-specific chain combinations. Mutations in this gene are thought to be responsible for the symptoms of a subset of patients with Ehlers-Danlos syndrome type III. Messages of several sizes can be detected in northern blots but sequence information cannot confirm the identity of the shorter messages. [provided by RefSeq, Jul 2008]

Chromosome

19

Cytoband

p13.2

Chromosome location (bp)

9959561 - 10010471

Protein evidence

Evidence at protein level (all genes)

Ensembl

ENSG00000080573 (version 78.38)

Entrez gene

50509

UniProt

P25940 (UniProt - Evidence at protein level)

neXtProt

NX_P25940

Antibodypedia

COL5A3 antibodies
 

PROTEIN VIEW

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COL5A3-001
 
 
 
 
 

PROTEIN INFORMATION

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Splice variant

Ensembl

UniProt

Protein class

Gene ontology

Length
(aa)

Molecular mass
(kDa)

Signal peptide
(predicted)

Transmembrane regions
(predicted)

COL5A3-001 ENSP00000264828
ENST00000264828
P25940
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