MCCC1

GENE INFORMATION

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Gene name

MCCC1 (HGNC Symbol)

Synonyms

MCCA

Description

Methylcrotonoyl-CoA carboxylase 1 (alpha) (HGNC Symbol)

Entrez gene summary

This gene encodes the large subunit of 3-methylcrotonyl-CoA carboxylase. This enzyme functions as a heterodimer and catalyzes the carboxylation of 3-methylcrotonyl-CoA to form 3-methylglutaconyl-CoA. Mutations in this gene are associated with 3-Methylcrotonylglycinuria, an autosomal recessive disorder of leucine catabolism. [provided by RefSeq, Jul 2008]

Chromosome

3

Cytoband

q27.1

Chromosome location (bp)

183015218 - 183116075

Protein evidence

Evidence at protein level (all genes)

Ensembl

ENSG00000078070 (version 78.38)

Entrez gene

56922

UniProt

Q96RQ3 (UniProt - Evidence at protein level)

neXtProt

NX_Q96RQ3

Antibodypedia

MCCC1 antibodies
 

PROTEIN VIEW

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MCCC1-001
 
MCCC1-002
 
MCCC1-003
 
MCCC1-201
 
MCCC1-202
 
 
 
 
 

PROTEIN INFORMATION

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Splice variant

Ensembl

UniProt

Protein class

Gene ontology

Length
(aa)

Molecular mass
(kDa)

Signal peptide
(predicted)

Transmembrane regions
(predicted)

MCCC1-001 ENSP00000265594
ENST00000265594
Q96RQ3
Show all »
Show » Show » 725 80.5 Yes 0
MCCC1-002 ENSP00000419898
ENST00000492597
E9PHF7
Show all »
Show » Show » 616 68.3 No 0
MCCC1-003 ENSP00000420433
ENST00000476176
E9PG35
Show all »
Show » Show » 598 66.5 No 0
MCCC1-201 ENSP00000441253
ENST00000539926
Show » Show » 575 64 No 0
MCCC1-202 ENSP00000480435
ENST00000610757
Show » Show » 575 64 No 0