CST7

GENE INFORMATION

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Gene name

CST7

Synonyms

Description

Cystatin F (leukocystatin) (HGNC Symbol)

Entrez gene summary

The cystatin superfamily encompasses proteins that contain multiple cystatin-like sequences. Some of the members are active cysteine protease inhibitors, while others have lost or perhaps never acquired this inhibitory activity. There are three inhibitory families in the superfamily, including the type 1 cystatins (stefins), type 2 cystatins and the kininogens. The type 2 cystatin proteins are a class of cysteine proteinase inhibitors found in a variety of human fluids and secretions. This gene encodes a glycosylated cysteine protease inhibitor with a putative role in immune regulation through inhibition of a unique target in the hematopoietic system. Expression of the protein has been observed in various human cancer cell lines established from malignant tumors. [provided by RefSeq, Jul 2008]

Chromosome

20

Cytoband

p11.21

Chromosome location (bp)

24949230 - 24959928

Protein evidence

Evidence at protein level (all genes)

Ensembl

ENSG00000077984 (version 78.38)

Entrez gene

8530

UniProt

O76096 (UniProt - Evidence at protein level)

neXtProt

NX_O76096

Antibodypedia

CST7 antibodies
 

PROTEIN VIEW

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CST7-001
 
 
 
 
 

PROTEIN INFORMATION

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Splice variant

Ensembl

UniProt

Protein class

Gene ontology

Length
(aa)

Molecular mass
(kDa)

Signal peptide
(predicted)

Transmembrane regions
(predicted)

CST7-001 ENSP00000420384
ENST00000480798
O76096
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