SMARCE1

GENE INFORMATION

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Gene name

SMARCE1 (HGNC Symbol)

Synonyms

BAF57

Description

SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily e, member 1 (HGNC Symbol)

Entrez gene summary

The protein encoded by this gene is part of the large ATP-dependent chromatin remodeling complex SWI/SNF, which is required for transcriptional activation of genes normally repressed by chromatin. The encoded protein, either alone or when in the SWI/SNF complex, can bind to 4-way junction DNA, which is thought to mimic the topology of DNA as it enters or exits the nucleosome. The protein contains a DNA-binding HMG domain, but disruption of this domain does not abolish the DNA-binding or nucleosome-displacement activities of the SWI/SNF complex. Unlike most of the SWI/SNF complex proteins, this protein has no yeast counterpart. [provided by RefSeq, Jul 2008]

Chromosome

17

Cytoband

q21.2

Chromosome location (bp)

40624962 - 40648508

Protein evidence

Evidence at protein level (all genes)

Ensembl

ENSG00000073584 (version 78.38)

Entrez gene

6605

UniProt

Q969G3 (UniProt - Evidence at protein level)

neXtProt

NX_Q969G3

Antibodypedia

SMARCE1 antibodies
 

PROTEIN VIEW

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SMARCE1-001
 
SMARCE1-006
 
SMARCE1-008
 
SMARCE1-009
 
SMARCE1-010
 
SMARCE1-012
 
SMARCE1-013
 
SMARCE1-014
 
SMARCE1-015
 
SMARCE1-016
 
SMARCE1-017
 
SMARCE1-018
 
SMARCE1-019
 
 » 
 
 
 
 

PROTEIN INFORMATION

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Splice variant

Ensembl

UniProt

Protein class

Gene ontology

Length
(aa)

Molecular mass
(kDa)

Signal peptide
(predicted)

Transmembrane regions
(predicted)

SMARCE1-001 ENSP00000323967
ENST00000348513
Q969G3
Show all »
Show » Show » 411 46.6 No 0
SMARCE1-006 ENSP00000463405
ENST00000474246
J3QL66
Show all »
Show » 77 8.3 No 0
SMARCE1-008 ENSP00000367039
ENST00000377808
Q969G3
Show all »
Show » Show » 328 38 No 0
SMARCE1-009 ENSP00000466608
ENST00000264640
H7C048
Show all »
Show » 177 20.5 No 0
SMARCE1-010 ENSP00000392958
ENST00000447024
H7C048
Show all »
Show » 157 18.3 No 0
SMARCE1-012 ENSP00000445370
ENST00000431889
B4DGM3
Show all »
Show » Show » 393 44.8 No 0
SMARCE1-013 ENSP00000462475
ENST00000580419
Q969G3
Show all »
Show » Show » 376 42.8 No 0
SMARCE1-014 ENSP00000464511
ENST00000578044
Q969G3
Show all »
Show » Show » 341 39.3 No 0
SMARCE1-015 ENSP00000411607
ENST00000400122
Q969G3
Show all »
Show » Show » 293 34.4 No 0
SMARCE1-016 ENSP00000464061
ENST00000580654
C0IMW8
Show all »
Show » 153 17.6 No 0
SMARCE1-017 ENSP00000462857
ENST00000577721
J3KT85
Show all »
Show » 101 12.1 No 0
SMARCE1-018 ENSP00000463216
ENST00000478349
J3QKS7
Show all »
Show » 288 33.4 No 0
SMARCE1-019 ENSP00000463282
ENST00000582955
J3QKX6
Show all »
Show » 129 14.6 No 0