ST6GALNAC1

GENE INFORMATION

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Gene name

ST6GALNAC1 (HGNC Symbol)

Synonyms

SIAT7A, ST6GalNAcI

Description

ST6 (alpha-N-acetyl-neuraminyl-2,3-beta-galactosyl-1,3)-N-acetylgalactosaminide alpha-2,6-sialyltransferase 1 (HGNC Symbol)

Entrez gene summary

Glycosylation of proteins affects cell-cell interaction, interactions with the matrix, and the functions of intracellular molecules. ST6GALNAC1 transfers a sialic acid, N-acetylneuraminic acid (NeuAc), in an alpha-2,6 linkage to O-linked GalNAc residues. The cancer-associated sialyl-Tn (sTn) antigen is formed by ST6GALNAC1-catalyzed sialylation of GalNAc residues on mucins (Ikehara et al., 1999 [PubMed 10536037]; Sewell et al., 2006 [PubMed 16319059]).[supplied by OMIM, Mar 2008]

Chromosome

17

Cytoband

q25.1

Chromosome location (bp)

76624761 - 76643838

Protein evidence

Evidence at protein level (all genes)

Ensembl

ENSG00000070526 (version 78.38)

Entrez gene

55808

UniProt

Q9NSC7 (UniProt - Evidence at transcript level)

neXtProt

NX_Q9NSC7

Antibodypedia

ST6GALNAC1 antibodies
 

PROTEIN VIEW

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ST6GALNAC1-001
 
ST6GALNAC1-006
 
ST6GALNAC1-010
 
 
 
 
 

PROTEIN INFORMATION

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Splice variant

Ensembl

UniProt

Protein class

Gene ontology

Length
(aa)

Molecular mass
(kDa)

Signal peptide
(predicted)

Transmembrane regions
(predicted)

ST6GALNAC1-001 ENSP00000156626
ENST00000156626
Q9NSC7
Show all »
Show » Show » 600 68.6 No 0
ST6GALNAC1-006 ENSP00000468784
ENST00000589992
K7EJA8
Show all »
Show » 63 7.2 No 1
ST6GALNAC1-010 ENSP00000466436
ENST00000590784
K7EMB6
Show all »
Show » Show » 153 17.5 No 0