MEF2A

GENERAL INFORMATION

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Gene name

MEF2A

Gene description

Myocyte enhancer factor 2A

Protein class

Cancer-related genes
Disease related genes
Predicted intracellular proteins
Transcription factors

Predicted localization

Intracellular

Number of transcripts

9
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HUMAN PROTEIN ATLAS INFORMATION

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RNA tissue category

HPA:Expressed in all
GTEx:Expressed in all

Protein evidence

Evidence at protein level

Protein localization

General nuclear expression.

ANTIBODY RELIABILITY

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Data reliability
description

Pending RNA-based expert annotation.

Data reliability

Supportive based on 2 antibodies.
HPA056563 , CAB004499
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RNA AND PROTEIN EXPRESSION SUMMARY

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RNA expression (FPKM) Protein expression (score)
Brain
Endocrine tissues
Bone marrow & immune system
Muscle tissues
Lung
Liver & gallbladder
Pancreas
Gastrointestinal tract
Kidney & urinary bladder
Male tissues
Female tissues
Adipose & soft tissue
Skin
Cerebral cortex

Lymph node

Skeletal muscle

Liver

Colon

Kidney

Testis



PROTEIN EXPRESSION OVERVIEW

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Organ

Expression



RNA EXPRESSION OVERVIEW

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HPA dataset
RNA tissue category:  Expressed in all

Organ

Expression

GTEx dataset
RNA tissue category:  Expressed in all

Organ

Expression



GENE INFORMATION

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Gene name

MEF2A (HGNC Symbol)

Synonyms

RSRFC4, RSRFC9

Description

Myocyte enhancer factor 2A (HGNC Symbol)

Entrez gene summary

The protein encoded by this gene is a DNA-binding transcription factor that activates many muscle-specific, growth factor-induced, and stress-induced genes. The encoded protein can act as a homodimer or as a heterodimer and is involved in several cellular processes, including muscle development, neuronal differentiation, cell growth control, and apoptosis. Defects in this gene could be a cause of autosomal dominant coronary artery disease 1 with myocardial infarction (ADCAD1). Several transcript variants encoding different isoforms have been found for this gene.[provided by RefSeq, Jan 2010]

Chromosome

15

Cytoband

q26.3

Chromosome location (bp)

99565417 - 99716466

Protein evidence

Evidence at protein level (all genes)

Ensembl

ENSG00000068305 (version 78.38)

Entrez gene

4205

UniProt

Q02078 (UniProt - Evidence at protein level)

neXtProt

NX_Q02078

Antibodypedia

MEF2A antibodies


PROTEIN BROWSER

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ENST00000338042
 
ENST00000354410
 
ENST00000449277
 
ENST00000557785
 
ENST00000557942
 
ENST00000558049
 
ENST00000558812
 
ENST00000559903
 
ENST00000560493
 
 
 
 


PROTEIN INFORMATION

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Splice variant

Ensembl

UniProt

Protein class

Gene ontology

Length
(aa)

Molecular mass
(kDa)

Signal peptide
(predicted)

Transmembrane regions
(predicted)

MEF2A-001 ENSP00000346389
ENST00000354410
Q02078
Show all »
Show » Show » 499 53.9 No 0
MEF2A-002 ENSP00000453441
ENST00000557785
Q02078
Show all »
Show » Show » 497 53.5 No 0
MEF2A-003 ENSP00000454120
ENST00000558812
Q02078
Show all »
Show » Show » 437 46.5 No 0
MEF2A-004 ENSP00000399460
ENST00000449277
Q02078
Show all »
Show » Show » 429 45.6 No 0
MEF2A-005 ENSP00000453095
ENST00000557942
Q02078
Show all »
Show » Show » 505 54.4 No 0
MEF2A-008 ENSP00000453478
ENST00000560493
H0YM62
Show all »
Show » Show » 85 10.1 No 0
MEF2A-009 ENSP00000452989
ENST00000559903
H0YKY6
Show all »
Show » Show » 77 9.2 No 0
MEF2A-010 ENSP00000454023
ENST00000558049
H0YNI2
Show all »
Show » Show » 38 4.6 No 0
MEF2A-201 ENSP00000337202
ENST00000338042
Q02078
Show all »
Show » Show » 497 53.5 No 0