DHX8

GENE INFORMATION

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Gene name

DHX8 (HGNC Symbol)

Synonyms

DDX8, HRH1, PRP22, PRPF22

Description

DEAH (Asp-Glu-Ala-His) box polypeptide 8 (HGNC Symbol)

Entrez gene summary

This gene is a member of the DEAH box polypeptide family. The encoded protein contains the DEAH (Asp-Glu-Ala-His) motif which is characteristic of all DEAH box proteins, and is thought to function as an ATP-dependent RNA helicase that regulates the release of spliced mRNAs from spliceosomes prior to their export from the nucleus. This protein may be required for the replication of human immunodeficiency virus type 1 (HIV-1). Alternative splicing results in multiple transcript variants. [provided by RefSeq, Oct 2014]

Chromosome

17

Cytoband

q21.31

Chromosome location (bp)

43483865 - 43544463

Protein evidence

Evidence at protein level (all genes)

Ensembl

ENSG00000067596 (version 78.38)

Entrez gene

1659

UniProt

Q14562 (UniProt - Evidence at protein level)

neXtProt

NX_Q14562

Antibodypedia

DHX8 antibodies
 

PROTEIN VIEW

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DHX8-001
 
DHX8-002
 
DHX8-004
 
DHX8-006
 
DHX8-007
 
 
 
 
 

PROTEIN INFORMATION

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Splice variant

Ensembl

UniProt

Protein class

Gene ontology

Length
(aa)

Molecular mass
(kDa)

Signal peptide
(predicted)

Transmembrane regions
(predicted)

DHX8-001 ENSP00000262415
ENST00000262415
Q14562
Show all »
Show » Show » 1220 139.3 Yes 0
DHX8-002 ENSP00000437886
ENST00000540306
F5H658
Show all »
Show » Show » 1181 134 Yes 0
DHX8-004 ENSP00000465178
ENST00000587574
Show » 33 3.8 No 0
DHX8-006 ENSP00000466900
ENST00000589898
K7END7
Show all »
Show » 138 16 No 0
DHX8-007 ENSP00000474654
ENST00000605777
S4R3S0
Show all »
Show » 78 8.6 No 0