FECH

GENE INFORMATION

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Gene name

FECH

Synonyms

Description

Ferrochelatase (HGNC Symbol)

Entrez gene summary

The protein encoded by this gene is localized to the mitochondrion, where it catalyzes the insertion of the ferrous form of iron into protoporphyrin IX in the heme synthesis pathway. Mutations in this gene are associated with erythropoietic protoporphyria. Two transcript variants encoding different isoforms have been found for this gene. A pseudogene of this gene is found on chromosome 3.[provided by RefSeq, May 2010]

Chromosome

18

Cytoband

q21.31

Chromosome location (bp)

57548283 - 57586772

Protein evidence

Evidence at protein level (all genes)

Ensembl

ENSG00000066926 (version 78.38)

Entrez gene

2235

UniProt

P22830 (UniProt - Evidence at protein level)

neXtProt

NX_P22830

Antibodypedia

FECH antibodies
 

PROTEIN VIEW

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FECH-001
 
FECH-002
 
FECH-005
 
FECH-006
 
FECH-009
 
FECH-010
 
 
 
 
 

PROTEIN INFORMATION

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Splice variant

Ensembl

UniProt

Protein class

Gene ontology

Length
(aa)

Molecular mass
(kDa)

Signal peptide
(predicted)

Transmembrane regions
(predicted)

FECH-001 ENSP00000262093
ENST00000262093
P22830
Show all »
Show » Show » 423 47.9 No 0
FECH-002 ENSP00000372326
ENST00000382873
P22830
Show all »
Show » Show » 429 48.6 No 0
FECH-005 ENSP00000466263
ENST00000592699
K7ELX4
Show all »
Show » Show » 326 37 No 0
FECH-006 ENSP00000465717
ENST00000585747
K7EKP7
Show all »
Show » Show » 165 18.1 No 0
FECH-009 ENSP00000467461
ENST00000591215
K7EPN2
Show all »
Show » Show » 90 10.2 No 0
FECH-010 ENSP00000465363
ENST00000591977
Show » Show » 143 16.2 No 0