ME1

GENE INFORMATION

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Gene name

ME1

Synonyms

Description

Malic enzyme 1, NADP(+)-dependent, cytosolic (HGNC Symbol)

Entrez gene summary

This gene encodes a cytosolic, NADP-dependent enzyme that generates NADPH for fatty acid biosynthesis. The activity of this enzyme, the reversible oxidative decarboxylation of malate, links the glycolytic and citric acid cycles. The regulation of expression for this gene is complex. Increased expression can result from elevated levels of thyroid hormones or by higher proportions of carbohydrates in the diet. [provided by RefSeq, Jul 2008]

Chromosome

6

Cytoband

q14.2

Chromosome location (bp)

83210389 - 83431071

Protein evidence

Evidence at protein level (all genes)

Ensembl

ENSG00000065833 (version 78.38)

Entrez gene

4199

UniProt

P48163 (UniProt - Evidence at protein level)

neXtProt

NX_P48163

Antibodypedia

ME1 antibodies
 

PROTEIN VIEW

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ME1-001
 
 
 
 
 

PROTEIN INFORMATION

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Splice variant

Ensembl

UniProt

Protein class

Gene ontology

Length
(aa)

Molecular mass
(kDa)

Signal peptide
(predicted)

Transmembrane regions
(predicted)

ME1-001 ENSP00000358719
ENST00000369705
P48163
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