DDX20

GENE INFORMATION

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Gene name

DDX20 (HGNC Symbol)

Synonyms

DP103, GEMIN3

Description

DEAD (Asp-Glu-Ala-Asp) box polypeptide 20 (HGNC Symbol)

Entrez gene summary

DEAD box proteins, characterized by the conserved motif Asp-Glu-Ala-Asp (DEAD), are putative RNA helicases. They are implicated in a number of cellular processes involving alteration of RNA secondary structure such as translation initiation, nuclear and mitochondrial splicing, and ribosome and spliceosome assembly. Based on their distribution patterns, some members of this family are believed to be involved in embryogenesis, spermatogenesis, and cellular growth and division. This gene encodes a DEAD box protein, which has an ATPase activity and is a component of the survival of motor neurons (SMN) complex. This protein interacts directly with SMN, the spinal muscular atrophy gene product, and may play a catalytic role in the function of the SMN complex on RNPs. [provided by RefSeq, Jul 2008]

Chromosome

1

Cytoband

p13.2

Chromosome location (bp)

111755245 - 111768016

Protein evidence

Evidence at protein level (all genes)

Ensembl

ENSG00000064703 (version 78.38)

Entrez gene

11218

UniProt

Q9UHI6 (UniProt - Evidence at protein level)

neXtProt

NX_Q9UHI6

Antibodypedia

DDX20 antibodies
 

PROTEIN VIEW

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DDX20-001
 
DDX20-002
 
 
 
 
 

PROTEIN INFORMATION

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Splice variant

Ensembl

UniProt

Protein class

Gene ontology

Length
(aa)

Molecular mass
(kDa)

Signal peptide
(predicted)

Transmembrane regions
(predicted)

DDX20-001 ENSP00000358716
ENST00000369702
Q9UHI6
Show all »
Show » Show » 824 92.2 Yes 0
DDX20-002 ENSP00000435660
ENST00000475700
E9PJ60
Show all »
Show » 432 49.4 Yes 0