TSPAN32

GENE INFORMATION

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Gene name

TSPAN32 (HGNC Symbol)

Synonyms

PHEMX, TSSC6

Description

Tetraspanin 32 (HGNC Symbol)

Entrez gene summary

This gene, which is a member of the tetraspanin superfamily, is one of several tumor-suppressing subtransferable fragments located in the imprinted gene domain of chromosome 11p15.5, an important tumor-suppressor gene region. Alterations in this region have been associated with Beckwith-Wiedemann syndrome, Wilms tumor, rhabdomyosarcoma, adrenocortical carcinoma, and lung, ovarian and breast cancers. This gene is located among several imprinted genes; however, this gene, as well as the tumor-suppressing subchromosomal transferable fragment 4, escapes imprinting. This gene may play a role in malignancies and diseases that involve this region, and it is also involved in hematopoietic cell function. Alternatively spliced transcript variants have been described, but their biological validity has not been determined. [provided by RefSeq, Jul 2008]

Chromosome

11

Cytoband

p15.5

Chromosome location (bp)

2301997 - 2318200

Protein evidence

Evidence at protein level (all genes)

Ensembl

ENSG00000064201 (version 78.38)

Entrez gene

10077

UniProt

Q96QS1 (UniProt - Evidence at transcript level)

neXtProt

NX_Q96QS1

Antibodypedia

TSPAN32 antibodies
 

PROTEIN VIEW

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TSPAN32-001
 
TSPAN32-003
 
TSPAN32-005
 
TSPAN32-014
 
TSPAN32-201
 
 
 
 
 

PROTEIN INFORMATION

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Splice variant

Ensembl

UniProt

Protein class

Gene ontology

Length
(aa)

Molecular mass
(kDa)

Signal peptide
(predicted)

Transmembrane regions
(predicted)

TSPAN32-001 ENSP00000182290
ENST00000182290
Q96QS1
Show all »
Show » Show » 320 34.6 No 3
TSPAN32-003 ENSP00000405205
ENST00000451520
D3YTD1
Show all »
Show » Show » 309 33.3 No 4
TSPAN32-005 ENSP00000370513
ENST00000381121
Q96QS1
Show all »
Show » Show » 253 27.8 No 3
TSPAN32-014 ENSP00000370509
ENST00000381117
G3XAG6
Show all »
Show » Show » 265 28.4 No 1
TSPAN32-201 ENSP00000482901
ENST00000612299
G3XAG6
Show all »
Show » Show » 265 28.4 No 1