DKK3

GENE INFORMATION

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Gene name

DKK3 (HGNC Symbol)

Synonyms

REIC, RIG

Description

Dickkopf WNT signaling pathway inhibitor 3 (HGNC Symbol)

Entrez gene summary

This gene encodes a protein that is a member of the dickkopf family. The secreted protein contains two cysteine rich regions and is involved in embryonic development through its interactions with the Wnt signaling pathway. The expression of this gene is decreased in a variety of cancer cell lines and it may function as a tumor suppressor gene. Alternative splicing results in multiple transcript variants encoding the same protein. [provided by RefSeq, Jul 2008]

Chromosome

11

Cytoband

p15.3

Chromosome location (bp)

11963106 - 12009769

Protein evidence

Evidence at protein level (all genes)

Ensembl

ENSG00000050165 (version 78.38)

Entrez gene

27122

UniProt

Q9UBP4 (UniProt - Evidence at protein level)

neXtProt

NX_Q9UBP4

Antibodypedia

DKK3 antibodies
 

PROTEIN VIEW

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DKK3-001
 
DKK3-002
 
DKK3-004
 
DKK3-010
 
DKK3-016
 
DKK3-017
 
 
 
 
 

PROTEIN INFORMATION

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Splice variant

Ensembl

UniProt

Protein class

Gene ontology

Length
(aa)

Molecular mass
(kDa)

Signal peptide
(predicted)

Transmembrane regions
(predicted)

DKK3-001 ENSP00000314910
ENST00000326932
Q9UBP4
Show all »
Show » Show » 350 38.4 Yes 0
DKK3-002 ENSP00000433112
ENST00000525493
F6SYF8
Show all »
Show » Show » 364 39.9 Yes 0
DKK3-004 ENSP00000379762
ENST00000396505
Q9UBP4
Show all »
Show » Show » 350 38.4 Yes 0
DKK3-010 ENSP00000435269
ENST00000533813
E9PKW6
Show all »
Show » Show » 235 25.7 Yes 0
DKK3-016 ENSP00000436645
ENST00000534511
E9PHY3
Show all »
Show » Show » 183 20 Yes 0
DKK3-017 ENSP00000431604
ENST00000529338
E9PKK9
Show all »
Show » 132 14.3 Yes 0