KITLG

GENE INFORMATION

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Gene name

KITLG (HGNC Symbol)

Synonyms

FPH2, Kitl, KL-1, MGF, SCF, SF

Description

KIT ligand (HGNC Symbol)

Entrez gene summary

This gene encodes the ligand of the tyrosine-kinase receptor encoded by the KIT locus. This ligand is a pleiotropic factor that acts in utero in germ cell and neural cell development, and hematopoiesis, all believed to reflect a role in cell migration. In adults, it functions pleiotropically, while mostly noted for its continued requirement in hematopoiesis. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008]

Chromosome

12

Cytoband

q21.32

Chromosome location (bp)

88492793 - 88580851

Protein evidence

Evidence at protein level (all genes)

Ensembl

ENSG00000049130 (version 78.38)

Entrez gene

4254

UniProt

P21583 (UniProt - Evidence at protein level)

neXtProt

NX_P21583

Antibodypedia

KITLG antibodies
 

PROTEIN VIEW

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KITLG-001
 
KITLG-002
 
KITLG-004
 
KITLG-005
 
KITLG-201
 
 
 
 
 

PROTEIN INFORMATION

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Splice variant

Ensembl

UniProt

Protein class

Gene ontology

Length
(aa)

Molecular mass
(kDa)

Signal peptide
(predicted)

Transmembrane regions
(predicted)

KITLG-001 ENSP00000054216
ENST00000347404
P21583
Show all »
Show » Show » 245 27.9 Yes 1
KITLG-002 ENSP00000228280
ENST00000228280
P21583
Show all »
Show » Show » 273 30.9 Yes 1
KITLG-004 ENSP00000475042
ENST00000552044
S4R442
Show all »
Show » Show » 24 2.7 No 0
KITLG-005 ENSP00000474021
ENST00000357116
S4R384
Show all »
Show » Show » 56 6.5 No 0
KITLG-201 ENSP00000479271
ENST00000613305
Show » 44 5.1 No 0