MAP4

GENE INFORMATION

? »

Gene name

MAP4

Synonyms

Description

Microtubule-associated protein 4 (HGNC Symbol)

Entrez gene summary

The protein encoded by this gene is a major non-neuronal microtubule-associated protein. This protein contains a domain similar to the microtubule-binding domains of neuronal microtubule-associated protein (MAP2) and microtubule-associated protein tau (MAPT/TAU). This protein promotes microtubule assembly, and has been shown to counteract destabilization of interphase microtubule catastrophe promotion. Cyclin B was found to interact with this protein, which targets cell division cycle 2 (CDC2) kinase to microtubules. The phosphorylation of this protein affects microtubule properties and cell cycle progression. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Aug 2008]

Chromosome

3

Cytoband

p21.31

Chromosome location (bp)

47850690 - 48089272

Protein evidence

Evidence at protein level (all genes)

Ensembl

ENSG00000047849 (version 78.38)

Entrez gene

4134

UniProt

P27816 (UniProt - Evidence at protein level)

neXtProt

NX_P27816

Antibodypedia

MAP4 antibodies
 

PROTEIN VIEW

? »
 
 
 
MAP4-001
 
MAP4-003
 
MAP4-005
 
MAP4-006
 
MAP4-007
 
MAP4-009
 
MAP4-011
 
MAP4-012
 
MAP4-013
 
MAP4-015
 
 
 
 
 

PROTEIN INFORMATION

? »

Splice variant

Ensembl

UniProt

Protein class

Gene ontology

Length
(aa)

Molecular mass
(kDa)

Signal peptide
(predicted)

Transmembrane regions
(predicted)

MAP4-001 ENSP00000353375
ENST00000360240
P27816
Show all »
Show » Show » 1152 121 No 0
MAP4-003 ENSP00000397414
ENST00000439356
P27816
Show all »
Show » Show » 99 10.4 No 0
MAP4-005 ENSP00000407602
ENST00000426837
E7EVA0
Show all »
Show » Show » 2297 245.4 No 0
MAP4-006 ENSP00000379083
ENST00000395734
P27816
Show all »
Show » Show » 1135 120 No 0
MAP4-007 ENSP00000402767
ENST00000434267
P27816
Show all »
Show » Show » 99 10.4 No 0
MAP4-009 ENSP00000373242
ENST00000383736
B5MEG9
Show all »
Show » Show » 712 75 No 0
MAP4-011 ENSP00000416743
ENST00000429422
Show » Show » 493 50.9 No 0
MAP4-012 ENSP00000334770
ENST00000335271
H0Y2V1
Show all »
Show » Show » 463 48.6 No 0
MAP4-013 ENSP00000409731
ENST00000420772
F8W9U4
Show all »
Show » Show » 828 88.3 No 0
MAP4-015 ENSP00000415689
ENST00000423088
Show » 290 31.5 No 0