DSG2

GENE INFORMATION

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Gene name

DSG2 (HGNC Symbol)

Synonyms

CDHF5

Description

Desmoglein 2 (HGNC Symbol)

Entrez gene summary

Desmosomes are cell-cell junctions between epithelial, myocardial, and certain other cell types. This gene product is a calcium-binding transmembrane glycoprotein component of desmosomes in vertebrate epithelial cells. Currently, three desmoglein subfamily members have been identified and all are members of the cadherin cell adhesion molecule superfamily. These desmoglein gene family members are located in a cluster on chromosome 18. This second family member is expressed in colon, colon carcinoma, and other simple and stratified epithelial-derived cell lines. Mutations in this gene have been associated with arrhythmogenic right ventricular dysplasia, familial, 10. [provided by RefSeq, Jul 2008]

Chromosome

18

Cytoband

q12.1

Chromosome location (bp)

31498043 - 31549008

Protein evidence

Evidence at protein level (all genes)

Ensembl

ENSG00000046604 (version 78.38)

Entrez gene

1829

UniProt

Q14126 (UniProt - Evidence at protein level)

neXtProt

NX_Q14126

Antibodypedia

DSG2 antibodies
 

PROTEIN VIEW

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DSG2-001
 
DSG2-002
 
 
 
 
 

PROTEIN INFORMATION

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Splice variant

Ensembl

UniProt

Protein class

Gene ontology

Length
(aa)

Molecular mass
(kDa)

Signal peptide
(predicted)

Transmembrane regions
(predicted)

DSG2-001 ENSP00000261590
ENST00000261590
Q14126
Show all »
Show » Show » 1118 122.3 Yes 1
DSG2-002 ENSP00000462503
ENST00000585206
J3KSI6
Show all »
Show » Show » 232 25.9 Yes 0