HSPA5

GENERAL INFORMATION

? »

Gene name

HSPA5

Gene description

Heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa)

Protein class

Disease related genes
Plasma proteins
Predicted secreted proteins

Predicted localization

Secreted

Number of transcripts

1
SHOW MORE

HUMAN PROTEIN ATLAS INFORMATION

? »

RNA tissue category

HPA:Expressed in all
GTEx:Expressed in all

Protein evidence

Evidence at protein level

Protein localization

Ubiquitous cytoplasmic expression.

ANTIBODY RELIABILITY

? »

Data reliability
description

Pending RNA-based expert annotation.

Data reliability

Supportive based on 3 antibodies.
HPA038845 , HPA038846 , CAB005221
SHOW MORE

RNA AND PROTEIN EXPRESSION SUMMARY

? »
RNA expression (FPKM) Protein expression (score)
Brain
Endocrine tissues
Bone marrow & immune system
Muscle tissues
Lung
Liver & gallbladder
Pancreas
Gastrointestinal tract
Kidney & urinary bladder
Male tissues
Female tissues
Adipose & soft tissue
Skin
Cerebral cortex

Lymph node

Liver

Colon

Kidney

Testis



PROTEIN EXPRESSION OVERVIEW

? »

Organ

Expression



RNA EXPRESSION OVERVIEW

? »
HPA dataset
RNA tissue category:  Expressed in all

Organ

Expression

GTEx dataset
RNA tissue category:  Expressed in all

Organ

Expression



GENE INFORMATION

? »

Gene name

HSPA5 (HGNC Symbol)

Synonyms

BiP, GRP78

Description

Heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) (HGNC Symbol)

Entrez gene summary

The protein encoded by this gene is a member of the heat shock protein 70 (HSP70) family. It is localized in the lumen of the endoplasmic reticulum (ER), and is involved in the folding and assembly of proteins in the ER. As this protein interacts with many ER proteins, it may play a key role in monitoring protein transport through the cell.[provided by RefSeq, Sep 2010]

Chromosome

9

Cytoband

q33.3

Chromosome location (bp)

125234853 - 125241330

Protein evidence

Evidence at protein level (all genes)

Ensembl

ENSG00000044574 (version 78.38)

Entrez gene

3309

UniProt

P11021 (UniProt - Evidence at protein level)

neXtProt

NX_P11021

Antibodypedia

HSPA5 antibodies


PROTEIN BROWSER

? »
 
 
 
ENST00000324460
 
 
 
 


PROTEIN INFORMATION

? »

Splice variant

Ensembl

UniProt

Protein class

Gene ontology

Length
(aa)

Molecular mass
(kDa)

Signal peptide
(predicted)

Transmembrane regions
(predicted)

HSPA5-001 ENSP00000324173
ENST00000324460
P11021
Show all »
Show » Show » 654 72.3 Yes 0