DNAH5

GENE INFORMATION

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Gene name

DNAH5 (HGNC Symbol)

Synonyms

CILD3, Dnahc5, HL1, KTGNR, PCD

Description

Dynein, axonemal, heavy chain 5 (HGNC Symbol)

Entrez gene summary

This gene encodes a dynein protein, which is part of a microtubule-associated motor protein complex consisting of heavy, light, and intermediate chains. This protein is an axonemal heavy chain dynein. It functions as a force-generating protein with ATPase activity, whereby the release of ADP is thought to produce the force-producing power stroke. Mutations in this gene cause primary ciliary dyskinesia type 3, as well as Kartagener syndrome, which are both diseases due to ciliary defects. [provided by RefSeq, Oct 2009]

Chromosome

5

Cytoband

p15.2

Chromosome location (bp)

13690331 - 13944543

Protein evidence

Evidence at protein level (all genes)

Ensembl

ENSG00000039139 (version 78.38)

Entrez gene

1767

UniProt

Q8TE73 (UniProt - Evidence at protein level)

neXtProt

NX_Q8TE73

Antibodypedia

DNAH5 antibodies
 

PROTEIN VIEW

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DNAH5-001
 
 
 
 
 

PROTEIN INFORMATION

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Splice variant

Ensembl

UniProt

Protein class

Gene ontology

Length
(aa)

Molecular mass
(kDa)

Signal peptide
(predicted)

Transmembrane regions
(predicted)

DNAH5-001 ENSP00000265104
ENST00000265104
Q8TE73
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