NSUN2

GENE INFORMATION

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Gene name

NSUN2 (HGNC Symbol)

Synonyms

FLJ20303, Misu, MRT5, TRM4

Description

NOP2/Sun RNA methyltransferase family, member 2 (HGNC Symbol)

Entrez gene summary

This gene encodes a methyltransferase that catalyzes the methylation of cytosine to 5-methylcytosine (m5C) at position 34 of intron-containing tRNA(Leu)(CAA) precursors. This modification is necessary to stabilize the anticodon-codon pairing and correctly translate the mRNA. Alternatively spliced transcript variants encoding different isoforms have been noted for this gene.[provided by RefSeq, Mar 2011]

Chromosome

5

Cytoband

p15.31

Chromosome location (bp)

6599239 - 6633291

Protein evidence

Evidence at protein level (all genes)

Ensembl

ENSG00000037474 (version 78.38)

Entrez gene

54888

UniProt

Q08J23 (UniProt - Evidence at protein level)

neXtProt

NX_Q08J23

Antibodypedia

NSUN2 antibodies
 

PROTEIN VIEW

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NSUN2-001
 
NSUN2-004
 
 
 
 
 

PROTEIN INFORMATION

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Splice variant

Ensembl

UniProt

Protein class

Gene ontology

Length
(aa)

Molecular mass
(kDa)

Signal peptide
(predicted)

Transmembrane regions
(predicted)

NSUN2-001 ENSP00000264670
ENST00000264670
Q08J23
Show all »
Show » Show » 767 86.5 No 0
NSUN2-004 ENSP00000420957
ENST00000506139
Q08J23
Show all »
Show » Show » 732 82.4 No 0