MYOM2

GENE INFORMATION

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Gene name

MYOM2

Synonyms

Description

Myomesin 2 (HGNC Symbol)

Entrez gene summary

The giant protein titin, together with its associated proteins, interconnects the major structure of sarcomeres, the M bands and Z discs. The C-terminal end of the titin string extends into the M line, where it binds tightly to M-band constituents of apparent molecular masses of 190 kD and 165 kD. The predicted MYOM2 protein contains 1,465 amino acids. Like MYOM1, MYOM2 has a unique N-terminal domain followed by 12 repeat domains with strong homology to either fibronectin type III or immunoglobulin C2 domains. Protein sequence comparisons suggested that the MYOM2 protein and bovine M protein are identical. [provided by RefSeq, Jul 2008]

Chromosome

8

Cytoband

p23.3

Chromosome location (bp)

2045040 - 2165552

Protein evidence

Evidence at protein level (all genes)

Ensembl

ENSG00000036448 (version 78.38)

Entrez gene

9172

UniProt

P54296 (UniProt - Evidence at protein level)

neXtProt

NX_P54296

Antibodypedia

MYOM2 antibodies
 

PROTEIN VIEW

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MYOM2-001
 
MYOM2-002
 
 
 
 
 

PROTEIN INFORMATION

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Splice variant

Ensembl

UniProt

Protein class

Gene ontology

Length
(aa)

Molecular mass
(kDa)

Signal peptide
(predicted)

Transmembrane regions
(predicted)

MYOM2-001 ENSP00000262113
ENST00000262113
P54296
Show all »
Show » Show » 1465 164.9 No 0
MYOM2-002 ENSP00000428396
ENST00000523438
Show » Show » 890 99.7 No 0