SNX1

GENE INFORMATION

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Gene name

SNX1 (HGNC Symbol)

Synonyms

HsT17379, MGC8664, SNX1A, Vps5

Description

Sorting nexin 1 (HGNC Symbol)

Entrez gene summary

This gene encodes a member of the sorting nexin family. Members of this family contain a phox (PX) domain, which is a phosphoinositide binding domain, and are involved in intracellular trafficking. This endosomal protein regulates the cell-surface expression of epidermal growth factor receptor. This protein also has a role in sorting protease-activated receptor-1 from early endosomes to lysosomes. This protein may form oligomeric complexes with family members. This gene results in three transcript variants encoding distinct isoforms. [provided by RefSeq, Jul 2008]

Chromosome

15

Cytoband

q22.31

Chromosome location (bp)

64094123 - 64146090

Protein evidence

Evidence at protein level (all genes)

Ensembl

ENSG00000028528 (version 78.38)

Entrez gene

6642

UniProt

Q13596 (UniProt - Evidence at protein level)

neXtProt

NX_Q13596

Antibodypedia

SNX1 antibodies
 

PROTEIN VIEW

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SNX1-001
 
SNX1-002
 
SNX1-003
 
SNX1-004
 
SNX1-008
 
SNX1-009
 
SNX1-010
 
 
 
 
 

PROTEIN INFORMATION

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Splice variant

Ensembl

UniProt

Protein class

Gene ontology

Length
(aa)

Molecular mass
(kDa)

Signal peptide
(predicted)

Transmembrane regions
(predicted)

SNX1-001 ENSP00000453785
ENST00000559844
Q13596
Show all »
Show » Show » 522 59.1 No 0
SNX1-002 ENSP00000453567
ENST00000561026
Q13596
Show all »
Show » Show » 457 51.8 No 0
SNX1-003 ENSP00000261889
ENST00000261889
Q13596
Show all »
Show » Show » 557 63.1 No 0
SNX1-004 ENSP00000452651
ENST00000560829
H0YK42
Show all »
Show » Show » 304 35.6 No 0
SNX1-008 ENSP00000452652
ENST00000559061
Show » 19 2.2 No 0
SNX1-009 ENSP00000452668
ENST00000558040
H0YK58
Show all »
Show » Show » 128 13.6 No 0
SNX1-010 ENSP00000452931
ENST00000560861
H0YKT3
Show all »
Show » Show » 70 8.4 No 0