VIM

GENE INFORMATION

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Gene name

VIM

Synonyms

Description

Vimentin (HGNC Symbol)

Entrez gene summary

This gene encodes a member of the intermediate filament family. Intermediate filamentents, along with microtubules and actin microfilaments, make up the cytoskeleton. The protein encoded by this gene is responsible for maintaining cell shape, integrity of the cytoplasm, and stabilizing cytoskeletal interactions. It is also involved in the immune response, and controls the transport of low-density lipoprotein (LDL)-derived cholesterol from a lysosome to the site of esterification. It functions as an organizer of a number of critical proteins involved in attachment, migration, and cell signaling. Mutations in this gene causes a dominant, pulverulent cataract.[provided by RefSeq, Jun 2009]

Chromosome

10

Cytoband

p13

Chromosome location (bp)

17228259 - 17237593

Protein evidence

Evidence at protein level (all genes)

Ensembl

ENSG00000026025 (version 78.38)

Entrez gene

7431

UniProt

P08670 (UniProt - Evidence at protein level)

neXtProt

NX_P08670

Antibodypedia

VIM antibodies
 

PROTEIN VIEW

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VIM-001
 
VIM-008
 
VIM-201
 
 
 
 
 

PROTEIN INFORMATION

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Splice variant

Ensembl

UniProt

Protein class

Gene ontology

Length
(aa)

Molecular mass
(kDa)

Signal peptide
(predicted)

Transmembrane regions
(predicted)

VIM-001 ENSP00000224237
ENST00000224237
P08670
Show all »
Show » Show » 466 53.7 No 0
VIM-008 ENSP00000391842
ENST00000421459
Q5JVS8
Show all »
Show » Show » 173 20 No 0
VIM-201 ENSP00000446007
ENST00000544301
P08670
Show all »
Show » Show » 466 53.7 No 0