HSD17B6

GENE INFORMATION

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Gene name

HSD17B6 (HGNC Symbol)

Synonyms

HSE, RODH, SDR9C6

Description

Hydroxysteroid (17-beta) dehydrogenase 6 (HGNC Symbol)

Entrez gene summary

The protein encoded by this gene has both oxidoreductase and epimerase activities and is involved in androgen catabolism. The oxidoreductase activity can convert 3 alpha-adiol to dihydrotestosterone, while the epimerase activity can convert androsterone to epi-androsterone. Both reactions use NAD+ as the preferred cofactor. This gene is a member of the retinol dehydrogenase family. [provided by RefSeq, Aug 2013]

Chromosome

12

Cytoband

q13.3

Chromosome location (bp)

56752161 - 56787790

Protein evidence

Evidence at protein level (all genes)

Ensembl

ENSG00000025423 (version 78.38)

Entrez gene

8630

UniProt

O14756 (UniProt - Evidence at protein level)

neXtProt

NX_O14756

Antibodypedia

HSD17B6 antibodies
 

PROTEIN VIEW

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HSD17B6-001
 
HSD17B6-002
 
HSD17B6-003
 
HSD17B6-004
 
HSD17B6-005
 
HSD17B6-006
 
HSD17B6-007
 
 
 
 
 

PROTEIN INFORMATION

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Splice variant

Ensembl

UniProt

Protein class

Gene ontology

Length
(aa)

Molecular mass
(kDa)

Signal peptide
(predicted)

Transmembrane regions
(predicted)

HSD17B6-001 ENSP00000318631
ENST00000322165
O14756
Show all »
Show » Show » 317 36 No 0
HSD17B6-002 ENSP00000450698
ENST00000555159
O14756
Show all »
Show » Show » 317 36 No 0
HSD17B6-003 ENSP00000451406
ENST00000554643
O14756
Show all »
Show » Show » 317 36 No 0
HSD17B6-004 ENSP00000451753
ENST00000555805
O14756
Show all »
Show » Show » 317 36 No 0
HSD17B6-005 ENSP00000452273
ENST00000554150
O14756
Show all »
Show » Show » 317 36 No 0
HSD17B6-006 ENSP00000452103
ENST00000556650
G3V508
Show all »
Show » 75 8.6 No 0
HSD17B6-007 ENSP00000451497
ENST00000554155
G3V3Y9
Show all »
Show » Show » 88 10.1 No 0