DEF6

GENE INFORMATION

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Gene name

DEF6 (HGNC Symbol)

Synonyms

IBP, SLAT, SWAP70L

Description

Differentially expressed in FDCP 6 homolog (mouse) (HGNC Symbol)

Entrez gene summary

DEF6, or IBP, is a guanine nucleotide exchange factor (GEF) for RAC (MIM 602048) and CDC42 (MIM 116952) that is highly expressed in B and T cells (Gupta et al., 2003 [PubMed 12923183]).[supplied by OMIM, Mar 2008]

Chromosome

6

Cytoband

p21.31

Chromosome location (bp)

35297852 - 35321771

Protein evidence

Evidence at protein level (all genes)

Ensembl

ENSG00000023892 (version 78.38)

Entrez gene

50619

UniProt

Q9H4E7 (UniProt - Evidence at protein level)

neXtProt

NX_Q9H4E7

Antibodypedia

DEF6 antibodies
 

PROTEIN VIEW

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DEF6-001
 
DEF6-002
 
 
 
 
 

PROTEIN INFORMATION

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Splice variant

Ensembl

UniProt

Protein class

Gene ontology

Length
(aa)

Molecular mass
(kDa)

Signal peptide
(predicted)

Transmembrane regions
(predicted)

DEF6-001 ENSP00000319831
ENST00000316637
Q9H4E7
Show all »
Show » Show » 631 73.9 No 0
DEF6-002 ENSP00000415357
ENST00000444278
Show » 129 14.7 No 0