CYP3A43

GENE INFORMATION

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Gene name

CYP3A43

Synonyms

Description

Cytochrome P450, family 3, subfamily A, polypeptide 43 (HGNC Symbol)

Entrez gene summary

This gene encodes a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are monooxygenases which catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids. The encoded protein has a low level of testosterone hydroxylase activity, and may play a role in aging mechanisms and cancer progression. This gene is part of a cluster of cytochrome P450 genes on chromosome 7q21.1. Alternate splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Jul 2013]

Chromosome

7

Cytoband

q22.1

Chromosome location (bp)

99828013 - 99866102

Protein evidence

Evidence at protein level (all genes)

Ensembl

ENSG00000021461 (version 78.38)

Entrez gene

64816

UniProt

Q9HB55 (UniProt - Evidence at protein level)

neXtProt

NX_Q9HB55

Antibodypedia

CYP3A43 antibodies
 

PROTEIN VIEW

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CYP3A43-001
 
CYP3A43-003
 
CYP3A43-005
 
CYP3A43-006
 
CYP3A43-013
 
CYP3A43-014
 
CYP3A43-201
 
 
 
 
 

PROTEIN INFORMATION

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Splice variant

Ensembl

UniProt

Protein class

Gene ontology

Length
(aa)

Molecular mass
(kDa)

Signal peptide
(predicted)

Transmembrane regions
(predicted)

CYP3A43-001 ENSP00000346887
ENST00000354829
Q9HB55
Show all »
Show » Show » 503 57.7 No 1
CYP3A43-003 ENSP00000416581
ENST00000417625
Q9HB55
Show all »
Show » Show » 393 44.8 No 2
CYP3A43-005 ENSP00000405557
ENST00000444905
C9JA26
Show all »
Show » Show » 167 19.1 No 0
CYP3A43-006 ENSP00000401521
ENST00000415413
E9PDL8
Show all »
Show » Show » 292 33.3 No 2
CYP3A43-013 ENSP00000312110
ENST00000312017
Q9HB55
Show all »
Show » Show » 420 48.3 No 1
CYP3A43-014 ENSP00000222382
ENST00000222382
Q9HB55
Show all »
Show » Show » 504 57.8 No 1
CYP3A43-201 ENSP00000345351
ENST00000342499
Q7Z2G5
Show all »
Show » Show » 126 14.6 No 2