SNAI2

GENERAL INFORMATION

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Gene name

SNAI2

Gene description

Snail family zinc finger 2

Protein class

Disease related genes
Predicted intracellular proteins
Transcription factors

Predicted localization

Intracellular

Number of transcripts

2
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HUMAN PROTEIN ATLAS INFORMATION

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RNA tissue category

HPA:Mixed
GTEx:Expressed in all

Protein evidence

Evidence at protein level

Protein localization

General nuclear expression.

ANTIBODY RELIABILITY

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Data reliability
description

Antibody staining mainly consistent with RNA expression data.

Data reliability

Supportive based on 1 antibody.
CAB011671
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RNA AND PROTEIN EXPRESSION SUMMARY

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RNA expression (FPKM) Protein expression (score)
Brain
Endocrine tissues
Bone marrow & immune system
Muscle tissues
Lung
Bronchus
N/A
N/A
Liver & gallbladder
Pancreas
Gastrointestinal tract
Kidney & urinary bladder
Male tissues
Female tissues
Adipose & soft tissue
Skin
Cerebral cortex

Lymph node

Liver

Colon

Kidney

Testis

Placenta



PROTEIN EXPRESSION OVERVIEW

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Organ

Expression



RNA EXPRESSION OVERVIEW

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HPA dataset
RNA tissue category:  Mixed

Organ

Expression

GTEx dataset
RNA tissue category:  Expressed in all

Organ

Expression



GENE INFORMATION

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Gene name

SNAI2 (HGNC Symbol)

Synonyms

SLUG, SLUGH1, SNAIL2

Description

Snail family zinc finger 2 (HGNC Symbol)

Entrez gene summary

This gene encodes a member of the Snail family of C2H2-type zinc finger transcription factors. The encoded protein acts as a transcriptional repressor that binds to E-box motifs and is also likely to repress E-cadherin transcription in breast carcinoma. This protein is involved in epithelial-mesenchymal transitions and has antiapoptotic activity. Mutations in this gene may be associated with sporatic cases of neural tube defects. [provided by RefSeq, Jul 2008]

Chromosome

8

Cytoband

q11.21

Chromosome location (bp)

48917690 - 48921740

Protein evidence

Evidence at protein level (all genes)

Ensembl

ENSG00000019549 (version 78.38)

Entrez gene

6591

UniProt

O43623 (UniProt - Evidence at protein level)

neXtProt

NX_O43623

Antibodypedia

SNAI2 antibodies


PROTEIN BROWSER

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ENST00000020945
 
ENST00000396822
 
 
 
 


PROTEIN INFORMATION

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Splice variant

Ensembl

UniProt

Protein class

Gene ontology

Length
(aa)

Molecular mass
(kDa)

Signal peptide
(predicted)

Transmembrane regions
(predicted)

SNAI2-001 ENSP00000380034
ENST00000396822
O43623
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Show » Show » 268 30 No 0
SNAI2-201 ENSP00000020945
ENST00000020945
O43623
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Show » Show » 268 30 No 0