CDKL3

GENE INFORMATION

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Gene name

CDKL3 (HGNC Symbol)

Synonyms

NKIAMRE

Description

Cyclin-dependent kinase-like 3 (HGNC Symbol)

Entrez gene summary

The protein encoded by this gene is a member of cyclin-dependent protein kinase (CDK) family. CDK family members are highly similar to the gene products of Saccharomyces cerevisiae cdc28, and Schizosaccharomyces pombe cdc2, and are known to be important regulators of cell cycle progression. This gene was identified as a gene absent in leukemic patients with chromosome 5q deletion. This loss may be an important determinant of dysmyelopoiesis. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Jul 2008]

Chromosome

5

Cytoband

q31.1

Chromosome location (bp)

134286350 - 134371047

Protein evidence

Evidence at protein level (all genes)

Ensembl

ENSG00000006837 (version 78.38)

Entrez gene

51265

UniProt

Q8IVW4 (UniProt - Evidence at protein level)

neXtProt

NX_Q8IVW4

Antibodypedia

CDKL3 antibodies
 

PROTEIN VIEW

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CDKL3-001
 
CDKL3-002
 
CDKL3-006
 
CDKL3-008
 
CDKL3-010
 
CDKL3-012
 
 
 
 
 

PROTEIN INFORMATION

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Splice variant

Ensembl

UniProt

Protein class

Gene ontology

Length
(aa)

Molecular mass
(kDa)

Signal peptide
(predicted)

Transmembrane regions
(predicted)

CDKL3-001 ENSP00000265334
ENST00000265334
Q8IVW4
Show all »
Show » Show » 592 67.5 No 0
CDKL3-002 ENSP00000428500
ENST00000523054
B4DX41
Show all »
Show » Show » 401 45.1 No 0
CDKL3-006 ENSP00000428689
ENST00000521118
E7ET86
Show all »
Show » Show » 590 67.2 No 0
CDKL3-008 ENSP00000430496
ENST00000523832
Q8IVW4
Show all »
Show » Show » 455 51.6 No 0
CDKL3-010 ENSP00000427964
ENST00000521755
E5RFT9
Show all »
Show » 44 4.9 No 0
CDKL3-012 ENSP00000427836
ENST00000518990
Show » 73 8.2 No 0