LTC4S

GENE INFORMATION

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Gene name

LTC4S (HGNC Symbol)

Synonyms

MGC33147

Description

Leukotriene C4 synthase (HGNC Symbol)

Entrez gene summary

The MAPEG (Membrane Associated Proteins in Eicosanoid and Glutathione metabolism) family includes a number of human proteins, several of which are involved the production of leukotrienes. This gene encodes an enzyme that catalyzes the first step in the biosynthesis of cysteinyl leukotrienes, potent biological compounds derived from arachidonic acid. Leukotrienes have been implicated as mediators of anaphylaxis and inflammatory conditions such as human bronchial asthma. This protein localizes to the nuclear envelope and adjacent endoplasmic reticulum. [provided by RefSeq, Jul 2008]

Chromosome

5

Cytoband

q35.3

Chromosome location (bp)

179793980 - 179796647

Protein evidence

Evidence at protein level (all genes)

Ensembl

ENSG00000213316 (version 78.38)

Entrez gene

4056

UniProt

Q16873 (UniProt - Evidence at protein level)

neXtProt

NX_Q16873

Antibodypedia

LTC4S antibodies
 

PROTEIN VIEW

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LTC4S-001
 
LTC4S-003
 
 
 
 
 

PROTEIN INFORMATION

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Splice variant

Ensembl

UniProt

Protein class

Gene ontology

Length
(aa)

Molecular mass
(kDa)

Signal peptide
(predicted)

Transmembrane regions
(predicted)

LTC4S-001 ENSP00000292596
ENST00000292596
Q16873
Show all »
Show » Show » 150 16.6 Yes 2
LTC4S-003 ENSP00000385627
ENST00000401985
B5MCC3
Show all »
Show » 93 10 No 1