E4F1

GENE INFORMATION

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Gene name

E4F1 (HGNC Symbol)

Synonyms

E4F

Description

E4F transcription factor 1 (HGNC Symbol)

Entrez gene summary

The zinc finger protein encoded by this gene is one of several cellular transcription factors whose DNA-binding activities are regulated through the action of adenovirus E1A. A 50-kDa amino-terminal product is generated from the full-length protein through proteolytic cleavage. The protein is differentially regulated by E1A-induced phosphorylation. The full-length gene product represses transcription from the E4 promoter in the absence of E1A, while the 50-kDa form acts as a transcriptional activator in its presence. Alternative splicing results in multiple transcripts encoding different proteins. [provided by RefSeq, Jan 2014]

Chromosome

16

Cytoband

p13.3

Chromosome location (bp)

2223566 - 2235742

Protein evidence

Evidence at protein level (all genes)

Ensembl

ENSG00000167967 (version 78.38)

Entrez gene

1877

UniProt

Q66K89 (UniProt - Evidence at protein level)

neXtProt

NX_Q66K89

Antibodypedia

E4F1 antibodies
 

PROTEIN VIEW

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E4F1-001
 
E4F1-002
 
E4F1-004
 
E4F1-008
 
 
 
 
 

PROTEIN INFORMATION

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Splice variant

Ensembl

UniProt

Protein class

Gene ontology

Length
(aa)

Molecular mass
(kDa)

Signal peptide
(predicted)

Transmembrane regions
(predicted)

E4F1-001 ENSP00000301727
ENST00000301727
Q66K89
Show all »
Show » Show » 784 83.5 No 0
E4F1-002 ENSP00000456760
ENST00000565090
H3BSL4
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Show » Show » 607 64 No 0
E4F1-004 ENSP00000457672
ENST00000564139
H3BUJ7
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Show » Show » 654 70.4 No 0
E4F1-008 ENSP00000454652
ENST00000565413
H3BN24
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Show » Show » 272 29.1 No 0