CDK5RAP2

GENE INFORMATION

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Gene name

CDK5RAP2 (HGNC Symbol)

Synonyms

C48, CEP215, FLJ10867, MCPH3

Description

CDK5 regulatory subunit associated protein 2 (HGNC Symbol)

Entrez gene summary

This gene encodes a regulator of CDK5 (cyclin-dependent kinase 5) activity. The protein encoded by this gene is localized to the centrosome and Golgi complex, interacts with CDK5R1 and pericentrin (PCNT), plays a role in centriole engagement and microtubule nucleation, and has been linked to primary microcephaly and Alzheimer's disease. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jan 2013]

Chromosome

9

Cytoband

q33.2

Chromosome location (bp)

120388869 - 120580170

Protein evidence

Evidence at protein level (all genes)

Ensembl

ENSG00000136861 (version 78.38)

Entrez gene

55755

UniProt

Q96SN8 (UniProt - Evidence at protein level)

neXtProt

NX_Q96SN8

Antibodypedia

CDK5RAP2 antibodies
 

PROTEIN VIEW

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CDK5RAP2-005
 
CDK5RAP2-008
 
CDK5RAP2-013
 
CDK5RAP2-014
 
CDK5RAP2-017
 
CDK5RAP2-201
 
 
 
 
 

PROTEIN INFORMATION

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Splice variant

Ensembl

UniProt

Protein class

Gene ontology

Length
(aa)

Molecular mass
(kDa)

Signal peptide
(predicted)

Transmembrane regions
(predicted)

CDK5RAP2-005 ENSP00000343818
ENST00000349780
Q96SN8
Show all »
Show » Show » 1893 215 No 0
CDK5RAP2-008 ENSP00000400395
ENST00000416449
B1AMJ5
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Show » Show » 1287 145.6 No 0
CDK5RAP2-013 ENSP00000409941
ENST00000425647
Q5JTU8
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Show » Show » 903 102.3 No 0
CDK5RAP2-014 ENSP00000353317
ENST00000360190
Q96SN8
Show all »
Show » Show » 1814 206.3 No 0
CDK5RAP2-017 ENSP00000419640
ENST00000482047
C9K0C9
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Show » 133 15.1 No 0
CDK5RAP2-201 ENSP00000354065
ENST00000360822
F8WBJ0
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Show » 1663 189.6 No 0