DNMT1

GENE INFORMATION

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Gene name

DNMT1 (HGNC Symbol)

Synonyms

CXXC9, DNMT, MCMT

Description

DNA (cytosine-5-)-methyltransferase 1 (HGNC Symbol)

Entrez gene summary

DNA (cytosine-5-)-methyltransferase 1 has a role in the establishment and regulation of tissue-specific patterns of methylated cytosine residues. Aberrant methylation patterns are associated with certain human tumors and developmental abnormalities. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Aug 2008]

Chromosome

19

Cytoband

p13.2

Chromosome location (bp)

10133345 - 10231286

Protein evidence

Evidence at protein level (all genes)

Ensembl

ENSG00000130816 (version 78.38)

Entrez gene

1786

UniProt

P26358 (UniProt - Evidence at protein level)

neXtProt

NX_P26358

Antibodypedia

DNMT1 antibodies
 

PROTEIN VIEW

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DNMT1-001
 
DNMT1-002
 
DNMT1-005
 
DNMT1-009
 
DNMT1-010
 
DNMT1-011
 
DNMT1-012
 
DNMT1-013
 
DNMT1-201
 
 
 
 
 

PROTEIN INFORMATION

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Splice variant

Ensembl

UniProt

Protein class

Gene ontology

Length
(aa)

Molecular mass
(kDa)

Signal peptide
(predicted)

Transmembrane regions
(predicted)

DNMT1-001 ENSP00000345739
ENST00000340748
P26358
Show all »
Show » Show » 1616 183.2 No 0
DNMT1-002 ENSP00000352516
ENST00000359526
P26358
Show all »
Show » Show » 1632 184.8 No 0
DNMT1-005 ENSP00000468062
ENST00000590619
Show » 78 8.6 No 0
DNMT1-009 ENSP00000465223
ENST00000588118
K7EJL0
Show all »
Show » Show » 255 28.3 No 0
DNMT1-010 ENSP00000465555
ENST00000586800
K7EKC3
Show all »
Show » 26 2.8 No 0
DNMT1-011 ENSP00000465993
ENST00000592342
K7ELB1
Show all »
Show » 94 10.4 No 0
DNMT1-012 ENSP00000467050
ENST00000588952
K7ENQ6
Show all »
Show » 119 13.6 No 0
DNMT1-013 ENSP00000468359
ENST00000592054
K7ERQ1
Show all »
Show » 71 7.8 No 0
DNMT1-201 ENSP00000440457
ENST00000540357
P26358
Show all »
Show » Show » 1280 144.5 No 0